Ketolide antibiotics
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United States of America Patent
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Apr 29, 2003
Grant Date -
May 30, 2002
app pub date -
Feb 26, 2001
filing date -
Mar 6, 2000
priority date (Note) -
Expired
status (Latency Note)
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Abstract
This invention relates to compounds of the formula 1 ##STR1## and to pharmaceutically acceptable salts, prodrugs, and solvates thereof wherein X.sup.1, R.sup.1, R.sup.2, R.sup.8, R.sup.9 and R.sup.10 are as defined herein. The compounds of formula 1 are antibacterial and antiprotozoal agents that may be used to treat various bacterial and protozoal infections and disorders related to such infections. The invention also relates to pharmaceutical compositions containing the compounds of formula 1 and to methods of treating bacterial and protozoal infections by administering the compounds of formula 1.
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