US Patent No: 6,558,612
Number of patents in Portfolio can not be more than 2000
Process for producing spherical biocompatible ceramic particles
Stats
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May 6, 2003
Issued date -
Nov 6, 1998
filing date -
09/187,924
serial no -
In Force
status
Importance
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Abstract
A permanent, biocompatible material for soft tissue augmentation. The biocompatible material comprises a matrix of smooth, round, finely divided, substantially spherical particles of a biocompatible ceramic material, close to or in contact with each other, which provide a scaffold or lattice for autogenous, three dimensional, randomly oriented, non-scar soft tissue growth at the augmentation site. The augmentation material can be homogeneously suspended in a biocompatible, resorbable lubricious gel carrier comprising a polysaccharide. This serves to improve the delivery of the augmentation material by injection to the tissue site where augmentation is desired. The augmentation material is especially suitable for urethral sphincter augmentation, for treatment of incontinence, for filling soft tissue voids, for creating soft tissue blebs, for the treatment of unilateral vocal cord paralysis, and for mammary implants. It can be injected intradermally, subcutaneously or can be implanted.
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First Claim
Related Publications
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International Classification(s)
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Cited Art
| Patent Info | (Count) | # Cites | Year |
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| 5,030,391 Process for the production of spherical particles of ceramics | 17 | 1988 | |
| 4,952,323 B2 microglobulin adsorbent | 14 | 1988 | |
| 5,441,635 Packing material for liquid chromatography | 11 | 1993 | |
| 6,306,297 Packing material for liquid chromatography and process for producing the same | 7 | 1995 | |
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| 5,143,724 Biocompatible viscoelastic gel slurries, their preparation and use | 63 | 1990 | |
| 5,246,698 Biocompatible viscoelastic gel slurries, their preparation and use | 45 | 1991 | |
| 5,399,351 Biocompatible viscoelastic gel slurries, their preparation and use | 60 | 1993 | |
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| 4,836,994 Calcium-phosphorus-apatite having novel properties and process for preparing the same | 15 | 1987 | |
| 5,108,956 Process for the preparation of microspherical sintered bodies of hydroxyapatite and a chromatographic packing material comprising the microspherical sintered bodies of hydroxyapatite | 13 | 1991 | |
| 5,205,928 Process for the preparation of microspherical sintered bodies of hydroxyapatite and a chromatographic packing material comprising the microspherical sintered bodies of hydroxyapatite | 22 | 1991 | |
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| 5,626,861 Polymeric-hydroxyapatite bone composite | 88 | 1994 | |
| 5,766,618 Polymeric-hydroxyapatite bone composite | 67 | 1997 | |
| 5,837,752 Semi-interpenetrating polymer networks | 72 | 1997 | |
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| 5,451,406 Tissue injectable composition and method of use | 137 | 1994 | |
| 5,792,478 Tissue injectable composition and method of use | 129 | 1996 | |
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| 5,480,644 Use of injectable biomaterials for the repair and augmentation of the anal sphincters | 40 | 1992 | |
| 5,490,984 Use of injectable biomaterials for the repair and augmentation of the anal sphincters | 136 | 1995 | |
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| 5,591,453 Incorporation of biologically active molecules into bioactive glasses | 81 | 1995 | |
| 5,861,176 Incorporation of biological molecules into bioactive glasses | 9 | 1996 | |
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| 4,518,430 Dental resptorative cement pastes | 105 | 1983 | |
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| 5,217,699 Calcium-phosphate type hydroxyapatite | 8 | 1991 | |
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| 5,853,398 Container with pivoting tube clamp | 17 | 1997 | |
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| 5,854,382 Bioresorbable compositions for implantable prostheses | 66 | 1997 | |
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| 5,709,875 Implantable biodegradable material and process for its production | 7 | 1994 | |
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| 5,149,368 Resorbable bioactive calcium phosphate cement | 127 | 1991 | |
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| 5,752,974 Injectable or implantable biomaterials for filling or blocking lumens and voids of the body | 220 | 1995 | |
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| 5,075,360 High-speed starch-based corrugating adhesive containing a carrier phase comprised of starch, modified starch or dextrin and polyvinyl alcohol | 16 | 1990 | |
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| 5,523,291 Injectable compositions for soft tissue augmentation | 34 | 1993 | |
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| 5,573,771 Medicinal bone mineral products | 61 | 1995 | |
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| 4,551,436 Fabrication of small dense silicon carbide spheres | 50 | 1984 | |
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| 6,165,514 Methods of enhancing repair, healing and augmentation of tissues and organs | 9 | 1998 | |
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| 4,803,075 Injectable implant composition having improved intrudability | 194 | 1986 | |
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| 6,211,459 Shielded bulk cable | 8 | 1995 | |
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| 4,440,754 Anti-inflammatory and anti-ulcer compounds and process | 26 | 1980 | |
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| 5,035,711 Transcutaneously implantable element | 36 | 1990 | |
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| 5,053,212 Intimate mixture of calcium and phosphate sources as precursor to hydroxyapatite | 128 | 1990 | |
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| 4,693,986 Ceramic process and products | 96 | 1987 | |
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| 5,034,352 Calcium phosphate materials | 64 | 1990 | |
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| 4,197,104 Magnetic tag process | 29 | 1978 | |
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| 5,126,141 Composition and method for post-surgical adhesion reduction with thermo-irreversible gels of polyoxyalkylene polymers and ionic polysaccharides | 89 | 1990 | |
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| 5,637,101 Quick release needle coupling system | 58 | 1995 | |
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| 5,152,836 Hydraulic calcium phosphate cement composition and cement composition containing hardening liquid | 46 | 1991 | |
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| 4,497,075 Filler for filling in defects or hollow portions of bones | 82 | 1982 | |
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| 5,067,965 Bio-osmotic gel for implant prostheses | 71 | 1990 | |
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| 5,702,677 Spherical hydroxyapatite particles and process for the production thereof | 20 | 1996 | |
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| 5,827,937 Polysaccharide gel composition | 17 | 1995 | |
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| 5,140,016 Method and composition for preventing surgical adhesions using a dilute solution of polymer | 44 | 1991 | |
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| 5,141,561 Bony or dental filling biomaterials and processes for preparation thereof | 10 | 1990 | |
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| 4,917,702 Bone replacement material on the basis of carbonate and alkali containing calciumphosphate apatites | 54 | 1988 | |
| 5,266,248 Method of producing hydroxylapatite base porous beads filler for an organism | 16 | 1992 | |
| 5,571,182 Textured micro implants | 84 | 1994 | |
Patent Citation Ranking
Maintenance Fees
| Fee | Large entity fee | small entity fee | micro entity fee | due date |
|---|---|---|---|---|
| 11.5 Year Payment | $7400.00 | $3700.00 | $1850.00 | Nov 6, 2014 |
| Fee | Large entity fee | small entity fee | micro entity fee |
|---|---|---|---|
| Surcharge - 11.5 year - Late payment within 6 months | $160.00 | $80.00 | $40.00 |
| Surcharge after expiration - Late payment is unavoidable | $700.00 | $350.00 | $175.00 |
| Surcharge after expiration - Late payment is unintentional | $1,640.00 | $820.00 | $410.00 |