Vaccine adjuvants
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United States of America Patent
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May 6, 2003
Issued Date -
N/A
app pub date -
Apr 29, 1999
filing date -
Apr 19, 1999
priority date (Note) -
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Abstract
The present invention relates to adjuvant compositions which are suitable to be used in vaccines. In particular, the adjuvant compositions of the present invention comprises a saponin and an immunostimulatory oligonucleotide, preferably the saponins used in said adjuvant combinations are haemolytic. Also provided by the present invention are vaccines comprising the adjuvants of the present invention and an antigen. Further provided are methods of manufacture of the adjuvants and vaccines of the present invention and their use as medicaments.
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