Waveforms for selective stimulation of central nervous system neurons
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United States of America Patent
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May 6, 2003
Grant Date -
Sep 5, 2002
app pub date -
Mar 5, 2001
filing date -
Sep 26, 2000
priority date (Note) -
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Abstract
Asymmetric charge-balanced stimulation waveforms are defined and used for CNS stimulation with selective stimulation of either neuronal cell bodies or axon fibers of passage in favor of the other. A pre-pulse is followed by an opposite polarity stimulation pulse, with the pre-pulse being relatively low-amplitude and long-duration as compared to the stimulation pulse. The pre-pulse and stimulation pulse are charge-balanced to prevent tissue damage and electrode corrosion. The polarity of the pre-pulse and stimulation pulse control the selectivity of stimulation with respect to neuronal cell bodies versus axon fibers of passage. The waveform used in the stimulation method optionally includes a zero-amplitude phase having a duration of 0 to 500 microseconds.
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