Liquefied embolic materials capable of sol-gel phase transition and their use
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United States of America Patent
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May 13, 2003
Grant Date -
N/A
app pub date -
Nov 7, 2000
filing date -
Sep 21, 2000
priority date (Note) -
Expired
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Abstract
Disclosed are liquefied embolic materials capable of sol-gel phase transition in response to in vivo conditions, including temperature, ionic strength, and pH, and their uses. The liquefied embolic materials are made of copolymers based on temperature-sensitive isopropylacrylamide and ionic strength- and/or pH-sensitive monomers. In addition to finding excellent applications in the embolotherapy, the embolic materials can be used as extracellular matrixes for cell culture and for drug-delivery systems for cancer therapy.
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