Transdermal active drug delivery system and method
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United States of America Patent
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May 13, 2003
Grant Date -
N/A
app pub date -
Aug 23, 2001
filing date -
Apr 23, 1995
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
A transdermal drug delivery system having at least one patch (20) with an electrosmotic, electro porous membrane (26) comprised of an inert biochemical substance which becomes actively electro-osmotic when an electric charge is passed through the membrane enabling a drug solution passing through to a skin surface to create an electroporative effect. The patch may be powered by a battery, an external power source (82), or self-powered by an auto-bio-fuel cell which acts as a battery during drug solution saturation. Multiple patches may be configured as a linked patch unit for use with a flexible cuff apparatus (70) to provide circumferential treatment of a body part. A network of supply tubes (66) may be connected to an external reservoir (68) to provide a slow supply of medicated fluid to each patch. A titration regulator (72) is in communication with the transdermal patch to regulate permanent flow to the skin.
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