Polymeric delivery formulations of leuprolide with improved efficacy
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United States of America Patent
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May 20, 2003
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N/A
app pub date -
Nov 13, 2000
filing date -
Oct 28, 1998
priority date (Note) -
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Abstract
The present invention is directed to a flowable composition that is suitable for use as a controlled release implant. The flowable composition includes a biodegradable thermoplastic polyester that is at least substantially insoluble in aqueous medium or body fluid. The flowable composition also includes a biocompatible polar aprotic solvent. The biocompatible polar aprotic solvent is miscible to dispersible in aqueous medium or body fluid. The flowable composition also includes leuprolide acetate.
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