Metalloporphyrins and their uses as imageable tumor-targeting agents for radiation therapy
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United States of America Patent
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May 20, 2003
Grant Date -
Feb 13, 2003
app pub date -
Jun 6, 2001
filing date -
Jun 6, 2001
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Abstract
The present invention covers halogenated derivatives of boronated porphyrins containing multiple carborane cages having the formula ##STR1## which selectively accumulate in neoplastic tissue within the irradiation volume and thus can be used in cancer therapies including, but not limited to, boron neutron- capture therapy and photodynamic therapy. The present invention also covers methods for using these halogenated derivatives of boronated porphyrins in tumor imaging and cancer treatment.
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