Z sharpening for fibre confocal microscopes
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United States of America Patent
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May 20, 2003
Grant Date -
Oct 25, 2001
app pub date -
Apr 3, 2001
filing date -
Apr 4, 2000
priority date (Note) -
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Abstract
A method and apparatus for image sharpening in confocal microscopy or endoscopy observation, the method comprising: collecting true confocal return light from an observational field of an object; focussing the true confocal return light into a core of a fiber wave-guide; collecting near confocal return light from a volume partially overlapping the observational field; focussing the near confocal return light so as to be transmitted principally in a cladding of the fiber wave-guide; separately detecting the true confocal return light and the near confocal return light to produce a true confocal output signal and a near confocal output signal; and adjusting the true confocal output signal on the basis of the near confocal output signal to substantially eliminate from the true confocal output signal a component due to the near confocal output signal; whereby the effective volume of the observational field is reduced and the resolution is effectively increased.
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