Ocular iontophoretic device and method for inhibiting vascular endothelial growth factor (VEGF) using the same
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United States of America Patent
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Jun 17, 2003
Grant Date -
Jul 25, 2002
app pub date -
Jan 22, 2001
filing date -
Jan 22, 2001
priority date (Note) -
Expired
status (Latency Note)
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Abstract
An ocular iontophoretic device for delivering an aptamer to an affected area of a living being's eye for inhibiting VEGF function therein, the device comprising an active electrode assembly associated with a matrix and/or reservoir, wherein the matrix and/or reservoir includes an aptamer capable of inhibiting VEGF function. A method for treating an affected area of a living being's eye, comprising the steps of: associating an aptamer with an ocular iontophoretic device; positioning at least a portion of an ocular iontophoretic device on the eye of the living being; and iontophoretically delivering the aptamer to an affected area of the living being's eye.
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