Method for producing 2-hydroxyisobutyric acid and methacrylic acid from acetone cyanohydrin
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United States of America Patent
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Jun 24, 2003
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N/A
app pub date -
Feb 5, 2002
filing date -
Feb 5, 2002
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Expired
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Abstract
The present invention relates to a method for producing 2-hydroxyisobutyric acid where acetone cyanohydrin is converted to 2-hydroxyisobutyric acid using an enzyme catalyst having nitrilase activity, or having a combination of nitrile hydratase and amidase activities. The invention also encompasses production of methacrylic acid wherein the 2-hydroxyisobutyric acid produced with the catalyst described is dehydrated to produce methacrylic acid.
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