14-methyl epothilone derivatives
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United States of America Patent
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Jun 24, 2003
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N/A
app pub date -
Nov 28, 2000
filing date -
Nov 20, 1998
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Abstract
Compounds of the invention include 14-mehtyl epothilone derivatives. More generally, preferred compounds of the invention are those that can be produced by altering the epothilone PKS genes as described herein and optionally by action of epothilone modification enzymes and/or by chemically modifying the resulting epothilones produces when those genes are expressed.
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