Cyclic salen-metal compounds: reactive oxygen species scavengers useful as antioxidants in the treatment and prevention of diseases
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United States of America Patent
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Jul 8, 2003
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app pub date -
Nov 28, 2000
filing date -
Nov 28, 2000
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Expired
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Abstract
This invention provides antioxidant cyclic salen-metal compounds, compositions of such antioxidant cyclic salen-metal compounds having superoxide activity, catalase activity and/or peroxidase activity and methods of using such antioxidant cyclic salen-metal compositions to treat or prevent a disease associated with cell or tissue damage produced by free radicals, such as superoxide. In one embodiment, the present invention provides cyclic salen-metal compounds having the following general formula: ##STR1##
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