US Patent No: 6,592,745

Number of patents in Portfolio can not be more than 2000

Method of using a small volume in vitro analyte sensor with diffusible or non-leachable redox mediator

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Abstract

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A sensor utilizing a non-leachable or diffusible redox mediator is described. The sensor includes a sample chamber to hold a sample in electrolytic contact with a working electrode, and in at least some instances, the sensor also contains a non-leachable or a diffusible second electron transfer agent. The sensor and/or the methods used produce a sensor signal in response to the analyte that can be distinguished from a background signal caused by the mediator. The invention can be used to determine the concentration of a biomolecule, such as glucose or lactate, in a biological fluid, such as blood or serum, using techniques such as coulometry, amperometry, and potentiometry. An enzyme capable of catalyzing the electrooxidation or electroreduction of the biomolecule is typically provided as a second electron transfer agent.

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Patent Owner(s)

Patent OwnerAddressTotal Patents
ABBOTT DIABETES CARE INC.ALAMEDA, CA766

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Colman, Fredric C Oakland, CA 235 24791
Feldman, Benjamin J Oakland, CA 192 15228
Funderburk, Jeffery V Fremont, CA 100 12688
Heller, Adam Austin, TX 446 55728
Heller, Ephraim Oakland, CA 239 25840
Krishnan, Rajesh Fremont, CA 69 6714
Mao, Fei Fremont, CA 146 8252
Vivolo, Joseph A San Francisco, CA 74 7740

Cited Art Landscape

Patent Info (Count) # Cites Year
 
Other [Check patent profile for assignment information] (16)
4,384,586 Method and apparatus for pH recording 239 1980
4,431,004 Implantable glucose sensor 682 1981
4,469,110 Device for causing a pinprick to obtain and to test a drop of blood 495 1982
4,538,616 Blood sugar level sensing and monitoring transducer 484 1983
4,633,878 Device for the automatic insulin or glucose infusion in diabetic subjects, based on the continuous monitoring of the patient's glucose, obtained without blood withdrawal 351 1984
4,595,011 Transdermal dosimeter and method of use 305 1984
4,685,463 Device for continuous in vivo measurement of blood glucose concentrations 402 1986
5,070,535 Transcutaneous power and signal transmission system and methods for increased signal transmission efficiency 268 1987
4,822,337 Insulin delivery method and apparatus 257 1987
4,871,351 Implantable medication infusion system 702 1987
4,776,944 Chemical selective sensors utilizing admittance modulated membranes 325 1987
4,909,908 Electrochemical cncentration detector method 289 1988
4,953,552 Blood glucose monitoring system 964 1989
5,205,920 Enzyme sensor and method of manufacturing the same 362 1990
5,337,747 Implantable device for estimating glucose levels 518 1993
5,830,341 Electrodes and metallo isoindole ringed compounds 200 1996
 
MINIMED TECHNOLOGIES LIMITED (1)
4,573,994 Refillable medication infusion apparatus 462 1981
 
BIOSPECIFIC TECHNOLOGIES, INC. (1)
4,534,356 Solid state transcutaneous blood gas sensors 342 1982
 
VICTORIA UNIVERSITY OF MANCHESTER, THE (3)
4,919,767 Sensor and method for analyte determination 238 1988
5,437,973 Enzyme-electrode sensor 195 1993
5,531,878 Sensor devices 624 1995
 
N.V. NEDERLANDSCHE APPARATENFABRIEK NEDAP (1)
5,372,133 Implantable biomedical sensor device, suitable in particular for measuring the concentration of glucose 565 1993
 
TERUMO KABUSHIKI KAISHA (3)
4,927,516 Enzyme sensor 485 1987
4,968,400 Enzyme sensor 208 1989
5,133,856 Ion sensor 244 1990
 
DUQUESNE UNIVERSITY OF THE HOLY GHOST (1)
5,387,327 Implantable non-enzymatic electrochemical glucose sensor 320 1992
 
Mitsubishi Pencil Kabushikikaisha (1)
5,380,422 Micro-electrode and method for preparing it 206 1992
 
Rijksuniversiteit te Groningen (1)
5,174,291 Process for using a measuring cell assembly for glucose determination 323 1990
 
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (2)
5,262,035 Enzyme electrodes 624 1989
5,593,852 Subcutaneous glucose electrode 922 1994
 
Mitsubishi Petrochemical Co., Ltd. (1)
5,096,560 Electrode for electrochemical detectors 185 1990
 
National Research Development Corporation (2)
4,318,784 Enzymatic processes 202 1980
4,655,885 Surface-modified electrode and its use in a bioelectrochemical process 246 1986
 
ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (3)
5,497,772 Glucose monitoring system 945 1993
5,660,163 Glucose sensor assembly 790 1995
5,791,344 Patient monitoring system 889 1996
 
ALLIED CORPORATION (1)
4,524,114 Bifunctional air electrode 247 1983
 
LOCKHEED MARTIN CORPORATION (1)
5,293,546 Oxide coated metal grid electrode structure in display devices 263 1991
 
YSI Incorporated (3)
4,356,074 Substrate specific galactose oxidase enzyme electrodes 265 1980
4,404,066 Method for quantitatively determining a particular substrate catalyzed by a multisubstrate enzyme 288 1982
5,217,595 Electrochemical gas sensor 254 1991
 
Evreka, Inc. (1)
4,436,094 Monitor for continuous in vivo measurement of glucose concentration 472 1982
 
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (6)
4,484,987 Method and membrane applicable to implantable sensor 377 1983
4,671,288 Electrochemical cell sensor for continuous short-term use in tissues and blood 786 1985
4,650,547 Method and membrane applicable to implantable sensor 412 1985
4,703,756 Complete glucose monitoring system with an implantable, telemetered sensor module 888 1986
4,781,798 Transparent multi-oxygen sensor array and method of using same 539 1987
4,890,620 Two-dimensional diffusion glucose substrate sensing electrode 617 1988
 
UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (1)
5,596,150 Capacitance probe for fluid flow and volume measurements 238 1995
 
E. HELLER & COMPANY, INC. (2)
6,143,164 Small volume in vitro analyte sensor 847 1998
6,120,676 Method of using a small volume in vitro analyte sensor 954 1999
 
THE CLEVELAND CLINIC FOUNDATION (1)
4,897,162 Pulse voltammetry 332 1988
 
UNIVERSITY OF KANSAS (1)
5,165,407 Implantable glucose sensor 837 1991
 
Sankyo Company, Limited (2)
4,871,440 Biosensor 456 1988
4,950,378 Biosensor 273 1988
 
EL PASO PRODUCTS COMPANY (1)
4,450,842 Solid state reference electrode 244 1981
 
R.E. STIFTUNG (1)
4,684,537 Process for the sensitization of an oxidation/reduction photocatalyst, and photocatalyst thus obtained 263 1985
 
ABBOTT LABORATORIES (2)
5,478,751 Self-venting immunodiagnositic devices and methods of performing assays 155 1994
5,520,787 Diagnostic flow cell device 276 1995
 
Abbott Point of Care Inc. (1)
5,514,253 Method of measuring gas concentrations and microfabricated sensing device for practicing same 239 1994
 
DANFOSS FLUID POWER A/S (1)
5,595,479 Hydraulic machine having teeth formed by rollers 52 1995
 
PHARMACONTROL CORPORATION (1)
4,750,496 Method and apparatus for measuring blood glucose concentration 367 1987
 
ABBOTT DIABETES CARE INC. (2)
6,071,391 Enzyme electrode structure 526 1997
* 6,338,790 Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator 581 1999
 
MINIMED INC., A DELAWARE CORPORATION D/B/A MINIMED TECHNOLOGIES (1)
5,390,671 Transcutaneous sensor insertion set 922 1994
 
INVERNESS MEDICAL TECHNOLOGY, INC. (1)
5,708,247 Disposable glucose test strips, and methods and compositions for making same 584 1996
 
California and Hawaiian Sugar Company (1)
4,552,840 Enzyme electrode and method for dextran analysis 285 1982
 
INVERNESS MEDICAL SWITZERLAND GMBH (1)
5,141,868 Device for use in chemical test procedures 619 1989
 
SRI INTERNATIONAL (1)
5,161,532 Integral interstitial fluid sensor 307 1990
 
Thorn EMI, plc (1)
5,206,145 Method of measuring the concentration of a substance in a sample solution 192 1991
 
Kyoto Daiichi Kagaku Co., Ltd. (6)
5,168,046 Method for determination of glucose concentration 188 1990
5,272,060 Method for determination of glucose concentration in whole blood 205 1992
5,382,346 Biosensor and method of quantitative analysis using the same 383 1993
5,496,453 Biosensor and method of quantitative analysis using the same 536 1994
5,720,862 Sensor and production method of and measurement method using the same 375 1996
5,781,455 Article of manufacture comprising computer usable medium for a portable blood sugar value measuring apparatus 254 1996
 
Mobil Oil Corporation (1)
5,364,797 Sensor device containing mesoporous crystalline material 289 1993
 
AJINOMOTO CO., INC. (1)
4,619,754 Chemically modified electrodes and their uses 361 1983
 
VIA MEDICAL CORPORATION (1)
5,271,815 Method for measuring glucose 277 1991
 
Radelkis Elektrokemiai Muszergyarto Szovetkezet (1)
4,375,399 Molecule selective sensor for industrial use and procedure for its preparation 234 1980
 
Dia-Med, Inc. (1)
4,365,637 Perspiration indicating alarm for diabetics 251 1980
 
ROCHE DIABETES CARE, INC. (8)
5,108,564 Method and apparatus for amperometric diagnostic analysis 475 1991
5,413,690 Potentiometric biosensor and the method of its use 343 1993
5,589,326 Osmium-containing redox mediator 283 1993
5,437,999 Electrochemical sensor 672 1994
5,846,702 Reagent including an osmium-containing redox mediator 210 1996
5,857,983 Methods and apparatus for sampling body fluid 426 1997
5,879,311 Body fluid sampling device and methods of use 421 1997
5,951,492 Methods and apparatus for sampling and analyzing body fluid 488 1997
 
MILES INC. (3)
4,938,860 Electrode for electrochemical sensors 344 1985
5,202,261 Conductive sensors and their use in diagnostic assays 448 1991
5,250,439 Use of conductive sensors in diagnostic assays 382 1992
 
EVOQUA WATER TECHNOLOGIES LLC (1)
5,958,779 Coulometric analysis 50 1996
 
Legacy Good Samaritan Hospital and Medical Center (1)
5,711,861 Device for monitoring changes in analyte concentration 666 1995
 
NOVO NORDISK A/S (1)
5,680,858 Method and apparatus for in vivo determination of the concentration in a body fluid of metabolically significant substances 367 1995
 
JOSLIN DIABETES CENTER, INC. (1)
4,340,458 Glucose sensor 272 1980
 
SHARP KABUSHIKI KAISHA (1)
5,140,393 Sensor device 229 1990
 
OHMICRON TECHNOLOGY, INC. (1)
4,444,892 Analytical device having semiconductive organic polymeric element associated with analyte-binding substance 262 1982
 
NOVOZYMES A/S (1)
5,741,688 Alkaline glucose oxidase obtained from cladosporium oxysporum 184 1995
 
CB-CARMEL BIOTECHNOLOGY LTD. (2)
5,101,814 System for monitoring and controlling blood glucose 672 1989
5,368,028 System for monitoring and controlling blood and tissue constituent levels 372 1993
 
Active Protective Technologies, Inc. (5)
2005/0067,816 Method and apparatus for body impact protection 16 2004
2005/0067,816 Method and apparatus for body impact protection 16 2004
2005/0067,816 Method and apparatus for body impact protection 16 2004
2005/0067,816 Method and apparatus for body impact protection 16 2004
2005/0067,816 Method and apparatus for body impact protection 16 2004
 
BOEHRINGER MANNHEIM GMBH (5)
5,096,836 Diagnostic test carrier 219 1990
5,310,885 Process for immobilizing a protein containing substance on a solid phase 193 1992
5,286,362 Method and sensor electrode system for the electrochemical determination of an analyte or an oxidoreductase as well as the use of suitable compounds therefor 454 1993
5,507,288 Analytical system for monitoring a substance to be analyzed in patient-blood 933 1995
5,834,224 Electrochemical sensor containing an enzyme linked to binding molecules bound to a noble metal surface 224 1995
 
BASF AKTIENGESELLSCHAFT (1)
4,526,661 Electrochemical hydrogenation of nicotinamide adenine dinucleotide 242 1983
 
Medisense, Inc. (8)
4,545,382 Sensor for components of a liquid mixture 688 1982
4,711,245 Sensor for components of a liquid mixture 618 1984
4,840,893 Electrochemical assay for nucleic acids and nucleic acid probes 438 1985
4,830,959 Electrochemical enzymic assay procedures 397 1986
5,126,034 Bioelectrochemical electrodes 459 1989
5,264,106 Enhanced amperometric sensor 370 1993
5,727,548 Strip electrode with screen printing 426 1995
5,628,890 Electrochemical sensor 849 1995
 
Otto Sensors Corporation (1)
4,682,602 Probe for medical application 277 1985
 
Endodermic Medical Technologies Company (1)
5,617,851 Ultrasonic transdermal system for withdrawing fluid from an organism and determining the concentration of a substance in the fluid 371 1995
 
PANASONIC CORPORATION (1)
5,264,103 Biosensor and a method for measuring a concentration of a substrate in a sample 603 1992
 
MITSUI ENGINEERING & SHIPBUILDING CO., LTD. (1)
5,059,290 Electroanalytical method 54 1989
 
QUESTSTAR MEDICAL, INC. (1)
4,637,403 Glucose medical monitoring system 727 1985
 
FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (1)
5,670,031 Electrochemical sensor 319 1995
 
HITACHI, LTD. (1)
4,795,707 Electrochemical sensor having three layer membrane containing immobilized enzymes 246 1985
 
BEND RESEARCH, INC. (1)
4,784,736 Functional, photochemically active, and chemically asymmetric membranes by interfacial polymerization of derivatized multifunctional prepolymers 252 1986
 
DISETRONIC LICENSING AG (2)
5,411,647 Techniques to improve the performance of electrochemical sensors 755 1994
5,695,623 Glucose measuring device 553 1994
 
I-STAT CORPORATION (2)
5,200,051 Wholly microfabricated biosensors and process for the manufacture and use thereof 675 1989
5,837,454 Process for the manufacture of wholly microfabricated biosensors 327 1995
 
Integ, Inc. (4)
5,582,184 Interstitial fluid collection and constituent measurement 813 1994
5,746,217 Interstitial fluid collection and constituent measurement 443 1995
5,682,233 Interstitial fluid sampler 452 1996
5,820,570 Interstitial fluid collection and constituent measurement 340 1997
 
THE REGENTS OF THE UNIVERSITY OF NEW MEXICO (2)
4,813,424 Long-life membrane electrode for non-ionic species 325 1987
4,986,271 Vivo refillable glucose sensor 443 1989
 
ENERGY, UNITED STATES DEPARTMENT OF (4)
4,461,691 Organic conductive films for semiconductor electrodes 265 1983
5,082,550 Enzyme electrochemical sensor electrode and method of making it 428 1989
5,208,154 Reversibly immobilized biological materials in monolayer films on electrodes 245 1991
5,227,042 Catalyzed enzyme electrodes 214 1992
 
Pacesetter, Inc. (2)
4,543,955 System for controlling body implantable action device 409 1983
4,815,469 Implantable blood oxygen sensor and method of use 397 1988
 
CLINICAL DIAGNOSTIC SYSTEMS INC. (1)
4,271,119 Capillary transport device having connected transport zones 138 1980
 
FIRST NATIONAL BANK OF BOSTON, THE (1)
4,759,828 Glucose electrode and method of determining glucose 501 1987
 
New Mexico State University Foundation, Inc. (1)
5,192,416 Method and apparatus for batch injection analysis 236 1991
 
HORIBA, LTD. (1)
4,923,586 Enzyme electrode unit 235 1989
 
CIBA CORNING DIAGNOSTICS CORP. (1)
5,198,367 Homogeneous amperometric immunoassay 244 1989
 
UOP LLC (1)
4,581,336 Surface-modified electrodes 270 1983
 
LABORATOIRES SERONO SA (1)
4,945,045 Electrochemical methods of assay 400 1988
 
Fresenius AG (1)
5,842,983 Biosensor 212 1996
 
Institute fur Diabetestechnologie Gemeinnutzige Forschungs- und Entwicklungsgesellschaft mbH (1)
4,919,141 Implantable electrochemical sensor 493 1988
 
Asulab S.A. (4)
5,378,628 Sensor for measuring the amount of a component in solution 407 1992
5,393,903 Mono, bis or tris(substituted 2,2'-bipyridine) iron, ruthenium, osmium or vanadium complexes and their methods of preparation 364 1992
5,395,504 Electrochemical measuring system with multizone sensors 427 1994
5,502,396 Measuring device with connection for a removable sensor 394 1994
 
SIEMENS AKTIENGESELLSCHAFT (3)
4,477,314 Method for determining sugar concentration 369 1983
4,759,371 Implantable, calibrateable measuring instrument for a body substance and a calibrating method 246 1987
5,552,027 Working electrode for electrochemical enzymatic sensor systems 188 1995
 
CAMBRIDGE LIFE SCIENCES PLC (2)
4,970,145 Immobilized enzyme electrodes 390 1988
5,846,744 Sensors based on polymer transformation 248 1996
 
FUJI ELECTRIC CO., LTD. (2)
4,407,959 Blood sugar analyzing apparatus 250 1981
4,483,924 System for controlling a printer in a blood sugar analyzer 199 1981
 
ARIZONA BOARD OF REGENTS (1)
4,935,345 Implantable microelectronic biochemical sensor incorporating thin film thermopile 369 1987
 
UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (1)
4,805,624 Low-potential electrochemical redox sensors 370 1987
 
New Oji Paper Co., Ltd. (1)
5,037,527 Reference electrode and a measuring apparatus using the same 191 1988
 
CRANFIELD BIOTECHNOLOGY LTD. (1)
5,525,511 Electrochemical biosensor stability 320 1993
 
SHIMADZU CORPORATION (1)
4,820,399 Enzyme electrodes 445 1985
 
Cardiac Pacemakers, Inc. (1)
4,679,562 Glucose sensor 311 1986
 
University Patents, Inc. (1)
4,440,175 Membrane electrode for non-ionic species 269 1981
 
MIGRATA U.K. LIMITED (1)
4,654,197 Cuvette for sampling and analysis 371 1984
 
MITSUBISHI DENKI KABUSHIKI KAISHA (1)
4,764,416 Electric element circuit using oxidation-reduction substances 242 1987
 
YACYNYCH, ALEXANDER M. (1)
5,286,364 Surface-modified electochemical biosensor 430 1991
 
GENETICS INSTITUTE, INC. (1)
4,758,323 Assay systems using more than one enzyme 364 1984
 
SENTRY MEDICAL PRODUCTS, INC., A CORP. OF MI (1)
4,848,351 Medical electrode assembly 233 1988
 
IMPERIAL CHEMICAL INDUSTRIES LIMITED (1)
4,935,105 Methods of operating enzyme electrode sensors 297 1989
 
PANASONIC HEALTHCARE HOLDINGS CO., LTD. (6)
5,582,697 Biosensor, and a method and a device for quantifying a substrate in a sample liquid using the same 609 1995
5,565,085 Method for quantifying specific compound 278 1995
5,575,895 Biosensor and method for producing the same 428 1995
5,650,062 Biosensor, and a method and a device for quantifying a substrate in a sample liquid using the same 437 1995
5,651,869 Biosensor 320 1996
6,004,441 Biosensor 314 1997
 
VALTION TEKNILLINEN TUTKIMUSKESKUS (1)
5,556,524 Electron-conducting molecular preparations 228 1995
 
AVL MEDICAL IMSTRUMENTS AG (1)
5,130,009 Sensor device 199 1990
 
MEDTRONIC MINIMED, INC. (4)
5,391,250 Method of fabricating thin film sensors 858 1994
5,569,186 Closed loop infusion pump system with removable glucose sensor 978 1994
5,568,806 Transcutaneous sensor insertion set 706 1995
5,586,553 Transcutaneous sensor insertion set 863 1995
 
Orasure Technologies, Inc. (1)
5,126,247 Method, system and devices for the assay and detection of biochemical molecules 233 1988
 
THERASENSE, INC. (3)
5,262,305 Interferant eliminating biosensors 653 1991
5,320,725 Electrode and method for the detection of hydrogen peroxide 600 1992
5,356,786 Interferant eliminating biosensor 769 1993
 
OMRON CORPORATION (1)
5,711,862 Portable biochemical measurement device using an enzyme sensor 230 1996
 
POLYTECHNIC UNIVERSITY (1)
5,089,112 Electrochemical biosensor based on immobilized enzymes and redox polymers 508 1990
 
CHIRON CORPORATION (1)
5,094,951 Production of glucose oxidase in recombinant systems 220 1989
 
BIOMEDIX, INC. (2)
5,695,947 Amperometric cholesterol biosensor 296 1995
6,033,866 Highly sensitive amperometric bi-mediator-based glucose biosensor 337 1997
 
THOMSON-CSF (1)
4,420,564 Blood sugar analyzer having fixed enzyme membrane sensor 375 1981
 
Omron Tateisi Electronics Co. (1)
4,894,137 Enzyme electrode 275 1987
 
DEXCOM, INC. (2)
4,757,022 Biological fluid measuring device 824 1987
4,994,167 Biological fluid measuring device 530 1988
 
SOLARCARE TECHNOLOGIES CORPORATION (1)
5,278,079 Sealing device and method for inhibition of flow in capillary measuring devices 216 1992
 
MEDTRONIC, INC. (1)
5,741,211 System and method for continuous monitoring of diabetes-related blood constituents 409 1995
 
MASSACHUSETTS INSTITUTE OF TECHNOLOGY (5)
4,721,601 Molecule-based microelectronic devices 282 1984
4,717,673 Microelectrochemical devices 251 1985
4,936,956 Microelectrochemical devices based on inorganic redox active material and method for sensing 208 1987
5,034,192 Molecule-based microelectronic devices 246 1989
5,109,850 Automatic blood monitoring for medication delivery method and apparatus 378 1991
 
Hypoguard Limited (1)
4,832,797 Enzyme electrode and membrane 251 1986
 
NEC CORPORATION (1)
5,082,786 Glucose sensor with gel-immobilized glucose oxidase and gluconolactonase 248 1988
 
ENTEGRIS, INC. (1)
2004/0121,494 Infrared thermopile detector system for semiconductor process monitoring and control 1 2003
 
Mallinckrodt Sensor Systems Inc. (1)
5,078,854 Polarographic chemical sensor with external reference electrode 196 1990
 
Nova Biomedical Corporation (1)
5,352,348 Method of using enzyme electrode 345 1992
 
KIDDE, INC. (1)
4,726,378 Adjustable magnetic supercutaneous device and transcutaneous coupling apparatus 253 1986
 
ROCHE DIAGNOSTICS CORPORATION (2)
5,288,636 Enzyme electrode system 537 1990
5,508,171 Assay method with enzyme electrode system 498 1994
 
MOLECULAR DEVICES CORPORATION (4)
4,911,794 Measuring with zero volume cell 400 1987
4,942,127 Polyredox couples in analyte determinations 203 1988
5,501,956 Polyredox couples in analyte determinations 191 1994
5,567,302 Electrochemical system for rapid detection of biochemical agents that catalyze a redox potential change 310 1995
 
Miles Laboratories, Inc. (3)
4,418,148 Multilayer enzyme electrode membrane 349 1981
4,427,770 High glucose-determining analytical element 244 1982
4,560,534 Polymer catalyst transducers 253 1983
 
Honeywell Inc. (1)
4,522,690 Electrochemical sensing of carbon monoxide 252 1983
 
THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (1)
5,580,527 Polymeric luminophores for sensing of oxygen 214 1994
 
Segars California Partners, LP (1)
5,804,048 Electrode assembly for assaying glucose 317 1996
 
CHILDREN'S HOSPITAL MEDICAL CENTER (1)
4,680,268 Implantable gas-containing biosensor and method for measuring an analyte such as glucose 514 1985
 
NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (1)
5,422,246 Electrode having a polymer coating with a redox enzyme bound thereto, the polymer coating being formed on the walls of pores extending through a porous membrane 229 1993
 
Hospira, Inc. (1)
5,326,449 Composite membrane 248 1993
 
BAXTER INTERNATIONAL INC. (1)
4,974,929 Fiber optical probe connector for physiologic measurement devices 435 1990
 
SIEMENS HEALTHCARE DIAGNOSTICS INC. (3)
5,494,562 Electrochemical sensors 550 1994
5,582,698 Sensor package 247 1995
5,770,028 Glucose and lactate sensors 216 1996
 
CASE WESTERN RESERVE UNIVERSITY (2)
4,571,292 Apparatus for electrochemical measurements 470 1982
4,655,880 Apparatus and method for sensing species, substances and substrates using oxidase 528 1983
 
LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (1)
5,120,421 Electrochemical sensor/detector system and method 365 1990
 
LIFESCAN, INC. (1)
5,526,120 Test strip with an asymmetrical end insuring correct insertion for measuring 405 1994
 
MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (6)
4,392,933 Electrochemical measuring apparatus comprising enzyme electrode 292 1982
4,897,173 Biosensor and method for making the same 491 1987
5,120,420 Biosensor and a process for preparation thereof 708 1989
5,229,282 Preparation of biosensor having a layer containing an enzyme, electron acceptor and hydrophilic polymer on an electrode system 422 1990
5,185,256 Method for making a biosensor 337 1991
5,192,415 Biosensor utilizing enzyme and a method for producing the same 450 1992
* Cited By Examiner

Patent Citation Ranking

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Patent Info (Count) # Cites Year
 
Other [Check patent profile for assignment information] (5)
* 2003/0155,237 Electrodes, methods, apparatuses comprising micro-electrode arrays 100 2002
* 2004/0031,682 Method for determining the concentration of an analyte in a liquid sample using small volume samples and fast test times 182 2003
* 2006/0007,017 Telemetered characteristic monitor system and method of using the same 39 2005
* 2006/0001,550 Telemetered characteristic monitor system and method of using the same 218 2005
* 2010/0297,743 COENZYME-BINDING GLUCOSE DEHYDROGENASE 6 2010
 
Yeongdong Electronics Co., Ltd. (1)
* 8,012,322 Biosensor for disease diagnosis 1 2008
 
ABBOTT DIABETES CARE INC. (160)
7,550,069 Small volume in vitro analyte sensor 5 2003
* 8,808,531 Small volume in vitro analyte sensor 0 2005
8,298,389 In vitro analyte sensor, and methods 1 2005
* 2007/0056,858 In vitro analyte sensor, and methods 12 2005
7,846,311 In vitro analyte sensor and methods of use 0 2005
* 2007/0068,807 In vitro analyte sensor and methods of use 126 2005
7,740,581 Methods of determining concentration of glucose 6 2005
* 2006/0025,662 Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator 142 2005
* 2007/0095,661 Method of making, and, analyte sensor 40 2005
7,918,975 Analytical sensors for biological fluid 0 2005
* 2007/0108,048 Sensors 126 2005
7,811,430 Biosensors and methods of making 1 2006
7,887,682 Analyte sensors and methods of use 6 2006
* 2007/0227,911 ANALYTE SENSORS AND METHODS OF USE 97 2006
8,728,297 Small volume in vitro analyte sensor 0 2006
7,699,973 Rapid analyte measurement assay 0 2006
9,259,175 Flexible patch for fluid delivery and monitoring body analytes 0 2006
8,158,081 Analyte monitoring devices 0 2006
7,740,580 Analyte monitoring 0 2006
* 2008/0099,332 Analyte Monitoring Devices 37 2006
8,186,044 Method of manufacturing small volume in vitro analyte sensors 0 2007
7,922,883 Biosensors and methods of using the same 1 2007
8,105,476 Integrated lancing and measurement device 1 2007
8,091,220 Methods of making small volume in vitro analyte sensors 0 2007
7,820,105 Analyte meter protectors and methods 0 2007
* 2008/0234,559 Analyte Meter Protectors and Methods 25 2007
7,988,845 Integrated lancing and measurement device and analyte measuring methods 1 2008
8,114,270 Small volume in vitro analyte sensor 0 2008
7,909,984 Small volume in vitro analyte sensor 2 2008
* 8,236,166 No calibration analyte sensors and methods 0 2008
* 2009/0011,449 NO CALIBRATION ANALYTE SENSORS AND METHODS 73 2008
8,080,153 Analyte determination methods and devices 2 2008
* 2009/0000,959 ANALYTE DETERMINATION METHODS AND DEVICES 7 2008
7,896,703 Strip connectors for measurement devices 6 2008
* 2010/0015,860 STRIP CONNECTORS FOR MEASUREMENT DEVICES 3 2008
8,142,642 Small volume in vitro analyte sensor 2 2008
7,906,009 Small volume in vitro analyte sensor 0 2008
8,758,583 Smart sensor ports and methods of using same 0 2009
* 2010/0274,181 SMART SENSOR PORTS AND METHODS OF USING SAME 3 2009
8,532,731 Methods of determining analyte concentration 0 2009
8,083,927 Analyte sensors and methods of use 1 2009
7,993,505 In vitro analyte sensor and methods of use 0 2009
7,967,962 Sensors 0 2009
7,811,432 Biosensors and methods of making 1 2009
* 2009/0321,256 BIOSENSORS AND METHODS OF MAKING 0 2009
8,236,254 Cap-linked test strip carrier for vial augmentation 2 2009
* 2010/0290,956 CAP-LINKED TEST STRIP CARRIER FOR VIAL AUGMENTATION 0 2009
8,437,827 Extruded analyte sensors and methods of using same 0 2009
8,298,158 Integrated devices having extruded electrode structures and methods of using same 0 2009
8,000,763 Integrated devices having extruded electrode structures and methods of using same 18 2009
* 2010/0326,843 EXTRUDED ANALYTE SENSORS AND METHODS OF USING SAME 16 2009
* 2010/0331,771 INTEGRATED DEVICES HAVING EXTRUDED ELECTRODE STRUCTURES AND METHODS OF USING SAME 4 2009
* 2010/0331,728 INTEGRATED DEVICES HAVING EXTRUDED ELECTRODE STRUCTURES AND METHODS OF USING SAME 3 2009
7,846,385 Analyte meter protectors and methods 0 2009
7,846,386 Analyte meter protectors and methods 0 2009
7,846,387 Analyte meter protectors and methods 0 2009
7,846,388 Analyte meter protectors and methods 0 2009
7,842,241 Analyte meter protectors and methods 0 2009
* 2010/0064,800 STRIP CONNECTORS FOR MEASUREMENT DEVICES 9 2009
* 2009/0270,706 ANALYTE MONITORING 0 2009
* 2009/0270,697 ANALYTE METER PROTECTORS AND METHODS 0 2009
* 2009/0264,725 ANALYTE METER PROTECTORS AND METHODS 0 2009
9,125,603 Analyte sensor ports 0 2009
* 2011/0040,208 INTEGRATED LANCET AND TEST STRIP AND METHODS OF MAKING AND USING SAME 0 2009
* 2011/0040,246 ANALYTE SENSOR PORTS 10 2009
8,357,276 Small volume test strips with large sample fill ports, supported test strips, and methods of making and using same 1 2009
8,701,282 Method for manufacturing a biosensor 0 2009
8,650,751 Methods of making small volume in vitro analyte sensors 0 2009
* 8,449,758 Small volume in vitro analyte sensor and methods of making 1 2009
8,425,758 Small volume in vitro analyte sensor and methods of making 0 2009
8,377,378 Small volume in vitro analyte sensor and methods of making 0 2009
8,372,261 Small volume in vitro analyte sensor and methods of making 0 2009
8,272,125 Method of manufacturing in vitro analyte sensors 0 2009
8,273,241 Small volume in vitro analyte sensor and methods of making 1 2009
8,268,144 Small volume in vitro analyte sensor and methods of making 0 2009
8,268,163 Small volume in vitro analyte sensor and methods of making 0 2009
8,262,996 Small volume in vitro sensor and methods of making 0 2009
8,226,815 Small volume in vitro sensor and methods of making 0 2009
8,221,685 Small volume in vitro sensor and methods of making 0 2009
8,211,363 Small volume in vitro analyte sensor and methods of making 0 2009
* 8,192,611 Small volume in vitro analyte sensor and methods of making 0 2009
8,187,895 Small volume in vitro analyte sensor and methods of making 0 2009
8,182,670 Small volume in vitro analyte sensor and methods of making 0 2009
8,182,671 Small volume in vitro analyte sensor and methods of making 2 2009
8,163,164 Small volume in vitro analyte sensor and methods of making 2 2009
8,153,063 Small volume in vitro analyte sensor and methods of making 1 2009
8,142,643 Small volume in vitro analyte sensor 0 2009
* 8,123,929 Small volume in vitro analyte sensor 0 2009
8,118,992 Small volume in vitro analyte sensor 0 2009
8,118,993 Small volume in vitro analyte sensor and methods of making 1 2009
8,114,271 Small volume in vitro analyte sensor 0 2009
8,087,162 Methods of making small volume in vitro analyte sensors 0 2009
8,083,924 Small volume in vitro analyte sensor and methods of making 0 2009
8,083,928 Small volume in vitro analyte sensor and methods of making 2 2009
8,083,929 Small volume in vitro sensor and methods of making 1 2009
* 2010/0012,523 Small Volume In Vitro Sensor and Methods of Making 0 2009
7,897,107 Analyte meter protectors and methods 0 2009
7,867,446 Analyte meter protectors and methods 0 2009
* 2010/0022,954 Analyte Meter Protectors and Methods 0 2009
8,282,578 Integrated lancet and analyte testing apparatus 2 2009
* 2010/0087,754 Integrated Lancet and Analyte Testing Apparatus 8 2009
9,326,707 Alarm characterization for analyte monitoring devices and systems 0 2009
7,914,742 Analyte meter protectors and methods 9 2009
7,896,704 Strip connectors for measurement devices 3 2009
* 2010/0065,426 Strip Connectors For Measurement Devices 3 2009
8,771,486 Smart sensor ports and methods of using same 0 2009
8,764,954 Smart sensor ports and methods of using same 0 2009
8,083,925 Analyte determination methods and devices 1 2009
* 2010/0270,149 Smart Sensor Ports and Methods of Using Same 5 2009
* 2010/0270,150 Smart Sensor Ports and Methods of Using Same 3 2009
* 2010/0159,570 Analyte Determination Methods and Devices 1 2009
8,828,330 Universal test strip port 0 2010
* 2011/0184,264 Universal Test Strip Port 14 2010
* 2010/0198,188 Devices and Methods for Metering Insoluble Active Agent Particles 0 2010
8,617,369 Rapid analyte measurement assay 0 2010
8,425,743 Small volume in vitro analyte sensor and methods of making 0 2010
9,101,303 Analyte sensor ports 0 2010
8,919,607 Analyte test strip vial 0 2010
7,914,335 Strip connectors for measurement devices 3 2010
8,211,280 Biosensors and methods of making 0 2010
8,757,386 Analyte test strip containers and inserts 0 2010
8,795,477 Methods of making, and, analyte sensor 1 2010
* 2011/0031,110 Methods of Making, and, Analyte Sensor 1 2010
9,031,630 Analyte sensors and methods of use 0 2010
8,080,205 Analyte meter protectors and methods 0 2011
8,241,486 Biosensors and methods of preparing same 0 2011
8,965,477 Analyte monitoring device and methods 0 2011
9,198,623 Devices, systems, and methods related to analyte monitoring and management 0 2011
9,085,790 Analyte sensors having temperature independent membranes 0 2011
8,475,732 Analyte measurement devices and systems, and components and methods related thereto 0 2011
D680454 Analyte meter and strip port 0 2011
8,702,928 Modular analyte measurement system with extendable strip port 0 2011
8,419,927 Analyte sensors and methods of use 0 2011
9,339,229 Analyte monitoring devices and methods 0 2011
8,414,759 Analyte determination methods and devices 0 2011
9,320,432 Analyte meter communication module 0 2011
8,414,762 Biosensors and methods of making 0 2012
9,289,164 Methods for generating hybrid analyte level output, and devices and systems related thereto 0 2012
9,113,828 Method and system for providing analyte monitoring 0 2012
8,652,320 Biosensors and methods of preparing same 0 2012
9,060,726 Integrated lancet and analyte testing apparatus 0 2012
8,887,911 Packages and kits for analyte monitoring devices, and methods related thereto 0 2012
8,679,311 Small volume test strips with large sample fill ports, supported test strips, and methods of making and using same 0 2013
8,632,731 Analyte measurement devices and systems, and components and methods related thereto 0 2013
9,273,337 Method for improving measurement accuracy and devices and systems related thereto 0 2013
9,063,076 Biosensors 0 2014
9,011,656 Small volume test strips with large sample fill ports, supported test strips, and methods of making and using same 0 2014
9,103,777 Modular analyte measurement system with extendable strip port 0 2014
9,341,591 Small volume in vitro analyte sensor 0 2014
9,316,609 Small volume in vitro analyte sensor 0 2014
9,291,592 Small volume in vitro analyte sensor 0 2014
9,234,863 Small volume in vitro analyte sensor 0 2014
9,207,201 Smart sensor ports and methods of using same 0 2014
9,290,839 Method of making, and, analyte sensor 0 2014
9,017,259 Integrated sample acquisition and analyte measurement device 0 2014
9,234,864 Small volume in vitro analyte sensor 0 2014
9,291,591 Universal test strip port 0 2014
9,332,933 Method and apparatus for providing analyte sensor insertion 0 2014
9,271,669 Method for integrated sample acquisition and analyte measurement device 0 2015
9,339,219 Devices, systems, and methods related to analyte monitoring and management 0 2015
 
MEDTRONIC MINIMED, INC. (160)
7,278,983 Physiological monitoring device for controlling a medication infusion device 471 2003
8,512,276 System for providing blood glucose measurements to an infusion device 7 2004
* 2005/0065,464 System for providing blood glucose measurements to an infusion device 201 2004
7,344,500 Sensing system with auxiliary display 124 2004
7,303,543 Medication infusion set 49 2004
7,704,229 Insertion device 12 2005
* 2006/0173,410 Insertion device 63 2005
* 2006/0184,104 Needle guard 28 2005
* 2006/0272,652 Virtual patient software system for educating and treating individuals with diabetes 176 2005
* 2007/0060,869 Controller device for an infusion pump 88 2005
* 2007/0060,870 Controller device for an infusion pump 60 2005
7,602,310 Telemetered characteristic monitor system and method of using the same 117 2005
7,324,012 Telemetered characteristic monitor system and method of using the same 249 2005
7,713,240 Modular external infusion device 26 2005
* 2007/0060,871 Modular external infusion device 59 2005
9,072,476 Flexible sensor apparatus 0 2005
7,725,148 Sensor with layered electrodes 0 2005
* 2007/0173,711 Sensor with layered electrodes 186 2005
7,774,038 Real-time self-calibrating sensor system and method 6 2005
7,621,893 Methods and apparatuses for detecting occlusions in an ambulatory infusion pump 50 2005
* 2007/0173,712 Method of and system for stabilization of sensors 31 2005
* 2007/0169,533 Methods and systems for detecting the hydration of sensors 12 2005
* 2007/0163,894 Real-time self-calibrating sensor system and method 14 2005
* 2006/0184,154 Methods and apparatuses for detecting occlusions in an ambulatory infusion pump 72 2005
7,942,844 Remote monitoring for networked fluid infusion systems 44 2006
7,737,581 Method and apparatus for predicting end of battery life 18 2006
* 2007/0093,786 Watch controller for a medical device 122 2006
* 2007/0033,074 Therapy management system 181 2006
7,766,873 Method and apparatus for detecting occlusions in an ambulatory infusion pump 39 2006
* 2007/0191,770 Method and apparatus for detecting occlusions in an ambulatory infusion pump 36 2006
* 2007/0100,222 Analyte sensing apparatus for hospital use 146 2006
* 2008/0139,910 Analyte sensor and method of using the same 154 2006
7,806,886 Apparatus and method for controlling insulin infusion with state variable feedback 41 2006
* 2007/0173,761 Apparatus and method for controlling insulin infusion with state variable feedback 179 2006
7,985,330 Method and system for detecting age, hydration, and functional states of sensors using electrochemical impedance spectroscopy 25 2006
* 2008/0183,060 Model predictive method and system for controlling and supervising insulin infusion 168 2007
8,073,008 Subnetwork synchronization and variable transmit synchronization techniques for a wireless medical device network 46 2007
* 2007/0244,383 Sensing system with auxiliary display 74 2007
8,114,268 Method and system for remedying sensor malfunctions detected by electrochemical impedance spectroscopy 21 2007
7,901,394 Physiological monitoring device for controlling a medication infusion device 89 2007
* 2008/0030,369 Telemetered characteristic monitor system and method of using the same 89 2007
8,162,876 Medication infusion set 0 2007
* 2008/0045,891 Medication infusion set 11 2007
7,727,148 Sensing system with auxiliary display 23 2007
8,114,269 System and method for determining the point of hydration and proper time to apply potential to a glucose sensor 19 2007
7,998,111 Methods and apparatuses for detecting occlusions in an ambulatory infusion pump 23 2008
* 2008/0221,522 Methods and apparatuses for detecting occlusions in an ambulatory infusion pump 9 2008
9,295,786 Needle protective device for subcutaneous sensors 0 2008
* 2009/0299,301 Needle protective device for subcutaneous sensors 3 2008
7,882,611 Method of making an analyte sensor 69 2008
* 2008/0313,896 Sensor with layered electrodes 13 2008
* 2009/0018,779 Flexible glucose analysis using varying time report deltas and configurable glucose target ranges 14 2008
7,815,622 Modular external infusion device 10 2008
* 2009/0048,574 Modular external infusion device 5 2008
8,208,973 System and method for variable beacon timing with wireless devices 8 2008
* 2009/0099,509 System for Providing Blood Glucose Measurements to an Infusion Device 9 2008
* 2009/0227,855 Controller device for an infusion pump 80 2008
9,330,237 Pattern recognition and filtering in a therapy management system 0 2008
8,348,886 Apparatus and method for controlling insulin infusion with state variable feedback 1 2009
* 2010/0114,015 Apparatus and method for controlling insulin infusion with state variable feedback 8 2009
8,545,443 Insertion device 1 2009
8,070,722 Insertion device 4 2009
8,344,847 Coordination of control commands in a medical device system having at least one therapy delivery device and at least one wireless controller device 7 2009
8,487,758 Medical device having an intelligent alerting scheme, and related operating methods 4 2009
8,182,447 Methods and apparatuses for detecting occlusions in an ambulatory infusion pump 10 2009
8,386,042 Omnidirectional accelerometer device and medical device incorporating same 15 2009
8,755,269 Ranking and switching of wireless channels in a body area network of medical devices 3 2009
8,394,058 Insertion device 0 2010
* 2010/0160,864 INSERTION DEVICE 0 2010
8,152,764 Modular external infusion device 13 2010
8,192,395 System for providing blood glucose measurements to an infusion device 21 2010
8,106,534 Method and apparatus for predicting end of battery life 8 2010
* 2010/0201,196 METHOD AND APPARATUS FOR PREDICTING END OF BATTERY LIFE 4 2010
8,622,954 Relay device for transferring information between a sensor system and a fluid delivery system 0 2010
* 2010/0280,442 Replay device for transferring information between a sensor system and a fluid delivery system 6 2010
8,062,257 Method and apparatus for detecting occlusions in an ambulatory infusion pump 18 2010
8,065,096 Method and apparatus for detecting occlusions in an ambulatory infusion pump 5 2010
* 2010/0274,592 THERAPY MANAGEMENT SYSTEM 11 2010
8,249,683 Real-time self-calibrating sensor system and method 2 2010
* 2010/0324,853 REAL-TIME SELF-CALIBRATING SENSOR SYSTEM AND METHOD 9 2010
8,348,923 Apparatus and method for controlling insulin infusion with state variable feedback 3 2010
8,182,462 Modular external infusion device 27 2010
8,602,992 Methods and systems for detecting the hydration of sensors 2 2010
8,591,416 Methods and systems for detecting the hydration of sensors 2 2010
8,532,732 Methods and systems for detecting the hydration of sensors 2 2010
* 2011/0054,281 METHODS AND SYSTEMS FOR DETECTING THE HYDRATION OF SENSORS 5 2010
* 2011/0048,941 METHODS AND SYSTEMS FOR DETECTING THE HYDRATION OF SENSORS 5 2010
* 2011/0010,104 METHODS AND SYSTEMS FOR DETECTING THE HYDRATION OF SENSORS 0 2010
* 2011/0010,105 METHODS AND SYSTEMS FOR DETECTING THE HYDRATION OF SENSORS 6 2010
8,603,032 Medical device with membrane keypad sealing element, and related manufacturing method 1 2010
8,603,033 Medical device and related assembly having an offset element for a piezoelectric speaker 0 2010
8,562,565 Battery shock absorber for a portable medical device 1 2010
8,105,268 Safety limits for closed-loop infusion pump control 6 2010
8,495,918 Sensor assembly and medical device incorporating same 9 2010
8,479,595 Sensor assembly and medical device incorporating same 7 2010
8,474,332 Sensor assembly and medical device incorporating same 9 2010
8,574,201 Syringe piston with check valve seal 0 2010
8,628,510 Monitoring the operating health of a force sensor in a fluid infusion device 7 2010
8,197,444 Monitoring the seating status of a fluid reservoir in a fluid infusion device 15 2010
8,850,687 Method of making a sensor 0 2010
8,850,688 Method of making a sensor with layered electrodes 0 2010
* 2011/0097,480 SENSOR WITH LAYERED ELECTRODES 5 2010
* 2011/0091,817 SENSOR WITH LAYERED ELECTRODES 0 2010
* 2011/0101,995 METHOD OF AND SYSTEM FOR STABILIZATION OF SENSORS 5 2011
* 2011/0106,480 METHOD OF AND SYSTEM FOR STABILIZATION OF SENSORS 5 2011
* 2011/0106,479 METHOD OF AND SYSTEM FOR STABILIZATION OF SENSORS 0 2011
8,614,596 Systems and methods for initializing a voltage bus and medical devices incorporating same 0 2011
9,101,305 Glucose sensor product and related manufacturing and packaging methods 0 2011
9,018,893 Power control techniques for an electronic device 0 2011
8,564,447 Battery life indication techniques for an electronic device 1 2011
8,647,296 Methods and apparatuses for detecting occlusions in an ambulatory infusion pump 0 2011
* 2011/0224,614 METHODS AND APPARATUSES FOR DETECTING OCCLUSIONS IN AN AMBULATORY INFUSION PUMP 6 2011
8,483,980 Method and apparatus for detecting occlusions in an ambulatory infusion pump 2 2011
8,663,201 Infusion device 0 2011
8,681,010 Method and apparatus for detecting occlusions in an ambulatory infusion pump 1 2011
8,267,893 Method and apparatus for detecting occlusions in an ambulatory infusion pump 6 2011
8,764,707 Insertion device 7 2011
9,056,162 Insertion device 0 2011
8,414,529 Insertion device 0 2011
8,784,370 Safety limits for closed-loop infusion pump control 7 2011
8,608,924 System and method for determining the point of hydration and proper time to apply potential to a glucose sensor 2 2011
8,574,216 Modular external infusion device 7 2011
9,125,607 Real-time self-calibrating sensor system and method 0 2011
8,454,576 Device and method for therapy calibration and safety response 3 2012
8,517,987 Modular external infusion device 7 2012
9,339,639 Sealing assembly for a fluid reservoir of a fluid infusion device 0 2012
9,272,125 Sealing assembly for a fluid reservoir of a fluid infusion device 0 2012
8,945,068 Fluid reservoir having a fluid delivery needle for a fluid infusion device 0 2012
8,900,206 Pressure vented fluid reservoir for a fluid infusion device 1 2012
8,870,829 Fluid infusion device and related sealing assembly for a needleless fluid reservoir 0 2012
8,864,726 Pressure vented fluid reservoir having a movable septum 0 2012
8,603,026 Dynamic pulse-width modulation motor control and medical device incorporating same 8 2012
8,603,027 Occlusion detection using pulse-width modulation and medical device incorporating same 8 2012
8,523,803 Motor health monitoring and medical device incorporating same 8 2012
8,668,672 Methods and apparatuses for detecting occlusions in an ambulatory infusion pump 0 2012
8,617,110 Methods and apparatuses for detecting occlusions in an ambulatory infusion pump 1 2012
8,414,557 Modular external infusion device 7 2012
8,568,357 System for providing blood glucose measurements to an infusion device 0 2012
8,690,855 Fluid reservoir seating procedure for a fluid infusion device 9 2012
9,333,292 Mechanically actuated fluid infusion device 0 2012
9,125,608 Real-time self-calibrating sensor system and method 0 2012
8,647,074 Method and apparatus for detecting occlusions in an ambulatory infusion pump 0 2012
8,808,269 Reservoir plunger position monitoring and medical device incorporating same 0 2012
8,870,818 Systems and methods for alignment and detection of a consumable component 0 2012
8,771,222 Apparatus and method for controlling insulin infusion with state variable feedback 7 2012
8,777,924 Apparatus and method for controlling insulin infusion with state variable feedback 7 2012
9,107,994 Systems for fluid reservoir retention 0 2013
9,033,924 Systems for fluid reservoir retention 0 2013
9,308,321 Infusion device having gear assembly initialization 0 2013
8,920,381 Infusion set with improved bore configuration 2 2013
9,220,840 Modular external infusion device 0 2013
9,259,528 Fluid infusion device with safety coupling 0 2013
9,333,294 Insertion device 0 2013
9,344,024 Occlusion detection using pulse-width modulation and medical device incorporating same 0 2013
9,011,371 Method and apparatus for detecting occlusions in an ambulatory infusion pump 0 2014
9,033,925 Methods and apparatuses for detecting occlusions in an ambulatory infusion pump 0 2014
8,864,739 Methods and apparatuses for detecting occlusions in an ambulatory infusion pump 0 2014
9,179,870 Method of making a sensor with layered electrodes 0 2014
9,107,999 Methods and apparatuses for detecting occlusions in an ambulatory infusion pump 0 2014
9,327,073 Method and apparatus for detecting occlusions in an ambulatory infusion pump 0 2015
 
Battelle Memorial Institute and Pharos, LLC (1)
* 2005/0029,121 Photolytic artificial lung 9 2004
 
PELIKAN TECHNOLOGIES, INC. (1)
8,197,423 Method and apparatus for penetrating tissue 0 2010
 
DEXCOM, INC. (10)
7,885,697 Transcutaneous analyte sensor 90 2005
8,133,178 Analyte sensor 12 2006
9,143,569 Systems and methods for processing, transmitting and displaying sensor data 1 2009
8,591,455 Systems and methods for customizing delivery of sensor data 0 2009
8,229,535 Systems and methods for blood glucose monitoring and alert delivery 2 2009
8,792,953 Transcutaneous analyte sensor 0 2010
9,237,864 Analyte sensors and methods of manufacturing same 0 2010
9,131,885 Analyte sensors and methods of manufacturing same 0 2010
8,828,201 Analyte sensors and methods of manufacturing same 0 2010
9,020,572 Systems and methods for processing, transmitting and displaying sensor data 1 2010
 
THORATEC LLC (2)
* 7,914,479 Photolytic artificial lung 1 2004
* 2008/0017,037 PHOTOLYTIC ARTIFICIAL LUNG 1 2007
 
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (1)
9,314,567 Electro-osmotic pumps, systems, methods, and compositions 0 2011
 
ISENSE ACQUISITION, LLC (2)
7,862,519 Easy-to-use multi-use body fluid specimen collection and analyte sensing assembly 2 2003
7,225,008 Multiple use analyte sensing assembly 103 2003
 
HENKEL CORPORATION (1)
* 2005/0039,848 Process for adhesive separation of bonded joints 0 2004
 
ASCENSIA DIABETES CARE HOLDINGS AG (10)
8,287,717 Voltammetric systems for assaying biological analytes 0 2005
8,026,104 Transient decay amperometry 0 2007
8,425,757 Gated amperometry 2 2007
8,404,100 Gated voltammetry 0 2008
8,470,604 Transient decay amperometry 0 2011
8,871,079 Voltammetric systems for assaying biological analytes 0 2012
8,647,489 Gated voltammetry devices 0 2013
8,877,035 Gated amperometry methods 0 2013
9,005,527 Transient decay amperometry biosensors 0 2013
9,110,013 Gated voltammetry methods 0 2013
 
AGAMATRIX, INC. (5)
* 2010/0219,083 Method and apparatus for processing electrochemical signals 0 2006
8,303,787 Method and apparatus for processing electrochemical signals 1 2010
* 2011/0147,210 Method and apparatus for processing electrochemical signals 0 2010
8,758,594 Analyte determination method and analyte meter 0 2012
9,234,862 Analyte determination method and analyte meter 0 2014
 
ROCHE DIABETES CARE, INC. (14)
7,407,811 System and method for analyte measurement using AC excitation 36 2003
* 7,287,318 Biosensor 113 2003
* 2004/0163,953 Biosensor 3 2003
8,206,565 System and method for coding information on a biosensor test strip 17 2004
8,058,077 Method for coding information on a biosensor test strip 0 2004
7,718,439 System and method for coding information on a biosensor test strip 40 2004
8,679,853 Biosensor with laser-sealed capillary space and method of making 0 2007
8,071,384 Control and calibration solutions and methods for their use 1 2008
8,148,164 System and method for determining the concentration of an analyte in a sample fluid 1 2009
8,293,538 System and method for coding information on a biosensor test strip 0 2010
8,298,828 System and method for determining the concentration of an analyte in a sample fluid 2 2012
8,507,289 System and method for coding information on a biosensor test strip 0 2012
8,586,373 System and method for determining the concentration of an analyte in a sample fluid 0 2012
* 8,997,330 Layered sensor for determining an analyte concentration 0 2012
 
Bayer Healthcare LLC, Diabetes Cares Division (1)
* 2008/0105,568 Voltammetric Systems For Assaying Biological Analytes 100 2005
 
SANOFI (3)
8,828,203 Printable hydrogels for biosensors 0 2005
8,808,201 Methods and apparatus for penetrating tissue 0 2008
9,261,476 Printable hydrogel for biosensors 0 2014
 
SANOFI-AVENTIS DEUTSCHLAND GMBH (121)
7,344,894 Thermal regulation of fluidic samples within a diagnostic cartridge 14 2001
7,780,631 Apparatus and method for penetration with shaft having a sensor for sensing penetration depth 1 2001
7,041,068 Sampling module device and method 306 2002
7,025,774 Tissue penetration device 169 2002
7,749,174 Method and apparatus for lancet launching device intergrated onto a blood-sampling cartridge 12 2002
7,699,791 Method and apparatus for improving success rate of blood yield from a fingerstick 0 2002
7,682,318 Blood sampling apparatus and method 101 2002
7,537,571 Integrated blood sampling analysis system with multi-use sampling module 101 2002
7,316,700 Self optimizing lancing device with adaptation means to temporal variations in cutaneous properties 108 2002
7,344,507 Method and apparatus for lancet actuation 140 2002
7,713,214 Method and apparatus for a multi-use body fluid sampling device with optical analyte sensing 90 2002
7,708,701 Method and apparatus for a multi-use body fluid sampling device 3 2002
7,226,461 Method and apparatus for a multi-use body fluid sampling device with sterility barrier release 115 2002
7,198,606 Method and apparatus for a multi-use body fluid sampling device with analyte sensing 340 2002
7,901,362 Method and apparatus for penetrating tissue 3 2002
7,717,863 Method and apparatus for penetrating tissue 2 2002
7,674,232 Method and apparatus for penetrating tissue 92 2002
7,582,099 Method and apparatus for penetrating tissue 100 2002
7,563,232 Method and apparatus for penetrating tissue 104 2002
7,547,287 Method and apparatus for penetrating tissue 103 2002
7,524,293 Method and apparatus for penetrating tissue 101 2002
7,491,178 Method and apparatus for penetrating tissue 110 2002
7,485,128 Method and apparatus for penetrating tissue 92 2002
7,410,468 Method and apparatus for penetrating tissue 102 2002
7,374,544 Method and apparatus for penetrating tissue 162 2002
7,371,247 Method and apparatus for penetrating tissue 110 2002
7,331,931 Method and apparatus for penetrating tissue 99 2002
7,297,122 Method and apparatus for penetrating tissue 100 2002
7,291,117 Method and apparatus for penetrating tissue 99 2002
7,244,265 Method and apparatus for penetrating tissue 100 2002
7,232,451 Method and apparatus for penetrating tissue 94 2002
7,229,458 Method and apparatus for penetrating tissue 154 2002
* 2003/0199,895 Method and apparatus for penetrating tissue 116 2002
7,258,693 Device and method for variable speed lancet 98 2003
8,267,870 Method and apparatus for body fluid sampling with hybrid actuation 1 2003
7,892,183 Method and apparatus for body fluid sampling and analyte sensing 9 2003
8,574,895 Method and apparatus using optical techniques to measure analyte levels 0 2003
8,262,614 Method and apparatus for fluid injection 1 2004
7,850,621 Method and apparatus for body fluid sampling and analyte sensing 16 2004
7,604,592 Method and apparatus for a point of care device 118 2004
8,282,576 Method and apparatus for an improved sample capture device 11 2004
8,668,656 Method and apparatus for improving fluidic flow and sample capture 0 2004
7,822,454 Fluid sampling device with improved analyte detecting member configuration 20 2005
8,721,671 Electric lancet actuator 0 2005
9,144,401 Low pain penetrating member 0 2005
8,211,037 Tissue penetration device 0 2005
8,206,317 Tissue penetration device 0 2005
8,016,774 Tissue penetration device 7 2005
7,981,055 Tissue penetration device 2 2005
7,850,622 Tissue penetration device 3 2005
8,360,991 Tissue penetration device 0 2005
8,216,154 Tissue penetration device 0 2005
8,641,643 Sampling module device and method 0 2006
8,403,864 Method and apparatus for penetrating tissue 0 2006
8,690,796 Method and apparatus for penetrating tissue 0 2006
7,938,787 Method and apparatus for penetrating tissue 1 2006
7,909,777 Method and apparatus for penetrating tissue 1 2006
8,579,831 Method and apparatus for penetrating tissue 0 2006
8,079,960 Methods and apparatus for lancet actuation 36 2006
8,062,231 Method and apparatus for penetrating tissue 0 2006
7,874,994 Method and apparatus for penetrating tissue 0 2006
8,007,446 Method and apparatus for penetrating tissue 0 2006
9,314,194 Tissue penetration device 0 2007
8,435,190 Method and apparatus for penetrating tissue 0 2007
7,875,047 Method and apparatus for a multi-use body fluid sampling device with sterility barrier release 3 2007
8,430,828 Method and apparatus for a multi-use body fluid sampling device with sterility barrier release 0 2007
8,382,682 Method and apparatus for penetrating tissue 0 2007
7,914,465 Method and apparatus for penetrating tissue 0 2007
7,833,171 Method and apparatus for penetrating tissue 1 2007
7,731,729 Method and apparatus for penetrating tissue 1 2007
8,414,503 Methods and apparatus for lancet actuation 0 2007
7,976,476 Device and method for variable speed lancet 0 2007
7,988,644 Method and apparatus for a multi-use body fluid sampling device with sterility barrier release 4 2007
7,901,365 Method and apparatus for penetrating tissue 43 2007
8,496,601 Methods and apparatus for lancet actuation 0 2007
8,491,500 Methods and apparatus for lancet actuation 15 2007
7,909,778 Method and apparatus for penetrating tissue 0 2007
8,202,231 Method and apparatus for penetrating tissue 0 2007
7,988,645 Self optimizing lancing device with adaptation means to temporal variations in cutaneous properties 1 2007
8,282,577 Method and apparatus for lancet launching device integrated onto a blood-sampling cartridge 0 2007
7,981,056 Methods and apparatus for lancet actuation 3 2007
8,123,700 Method and apparatus for lancet launching device integrated onto a blood-sampling cartridge 3 2007
7,909,775 Method and apparatus for lancet launching device integrated onto a blood-sampling cartridge 0 2007
8,197,421 Method and apparatus for penetrating tissue 15 2007
8,157,748 Methods and apparatus for lancet actuation 1 2008
8,652,831 Method and apparatus for analyte measurement test time 0 2008
8,641,644 Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means 0 2008
8,388,551 Method and apparatus for multi-use body fluid sampling device with sterility barrier release 0 2008
7,862,520 Body fluid sampling module with a continuous compression tissue interface surface 0 2008
8,784,335 Body fluid sampling device with a capacitive sensor 0 2008
8,372,016 Method and apparatus for body fluid sampling and analyte sensing 1 2008
7,892,185 Method and apparatus for body fluid sampling and analyte sensing 8 2008
8,360,992 Method and apparatus for penetrating tissue 0 2008
8,636,673 Tissue penetration device 0 2008
8,845,549 Method for penetrating tissue 0 2008
8,366,637 Method and apparatus for penetrating tissue 0 2008
9,339,612 Tissue penetration device 0 2008
8,562,545 Tissue penetration device 2 2008
8,337,421 Tissue penetration device 2 2008
8,235,915 Method and apparatus for penetrating tissue 0 2008
8,556,829 Method and apparatus for penetrating tissue 0 2009
8,702,624 Analyte measurement device with a single shot actuator 6 2010
8,439,872 Apparatus and method for penetration with shaft having a sensor for sensing penetration depth 0 2010
8,251,921 Method and apparatus for body fluid sampling and analyte sensing 0 2010
8,296,918 Method of manufacturing a fluid sampling device with improved analyte detecting member configuration 1 2010
8,206,319 Tissue penetration device 38 2010
9,226,699 Body fluid sampling module with a continuous compression tissue interface surface 0 2010
8,221,334 Method and apparatus for penetrating tissue 0 2010
8,965,476 Tissue penetration device 0 2011
8,679,033 Tissue penetration device 0 2011
8,622,930 Tissue penetration device 0 2011
8,382,683 Tissue penetration device 1 2012
8,905,945 Method and apparatus for penetrating tissue 0 2012
9,089,678 Method and apparatus for penetrating tissue 0 2012
8,945,910 Method and apparatus for an improved sample capture device 0 2012
9,034,639 Method and apparatus using optical techniques to measure analyte levels 4 2012
8,845,550 Tissue penetration device 0 2012
9,248,267 Tissue penetration device 0 2013
9,072,842 Method and apparatus for penetrating tissue 0 2013
9,186,468 Method and apparatus for penetrating tissue 0 2014
9,089,294 Analyte measurement device with a single shot actuator 0 2014
 
HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (4)
7,147,742 Method for accelerating the curing of adhesives 9 2001
6,855,760 Detachable adhesive compounds 15 2002
* 2003/0168,640 Method for accelerating the curing of adhesives 1 2003
7,407,704 Process for adhesive separation of bonded joints 1 2004
 
Nova Biomedical Corporation (2)
7,955,484 Glucose biosensor and method 5 2005
* 2007/0131,549 GLUCOSE BIOSENSOR AND METHOD 19 2005
 
APPLIED NANOTECH HOLDINGS, INC. (1)
* 2005/0244,811 Matrix array nanobiosensor 18 2004
 
NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (1)
* 2009/0093,695 BIOSENSOR 8 2006
 
ROCHE OPERATIONS LTD. (33)
7,276,146 Electrodes, methods, apparatuses comprising micro-electrode arrays 148 2002
* 2007/0170,055 ELECTRODES, METHODS, APPARATUSES COMPRISING MICRO-ELECTRODE ARRAYS 3 2002
7,276,147 Method for determining the concentration of an analyte in a liquid sample using small volume samples and fast test times 139 2003
* 7,597,793 System and method for analyte measurement employing maximum dosing time delay 19 2003
7,494,816 System and method for determining a temperature during analyte measurement 16 2003
7,488,601 System and method for determining an abused sensor during analyte measurement 30 2003
7,452,457 System and method for analyte measurement using dose sufficiency electrodes 24 2003
7,390,667 System and method for analyte measurement using AC phase angle measurements 28 2003
8,071,030 Test strip with flared sample receiving chamber 3 2004
7,829,023 Test strip with vent opening 27 2004
7,749,437 Method and reagent for producing narrow, homogenous reagent stripes 13 2004
7,727,467 Reagent stripe for test strip 24 2004
7,645,373 System and method for coding information on a biosensor test strip 15 2004
7,645,421 System and method for coding information on a biosensor test strip 18 2004
7,604,721 System and method for coding information on a biosensor test strip 20 2004
7,569,126 System and method for quality assurance of a biosensor test strip 8 2004
7,556,723 Electrode design for biosensor 5 2005
7,338,639 System and method for analyte measurement 154 2006
8,551,308 Biosensor and method of making 2 2008
8,287,703 Biosensor and method of making 8 2008
8,663,442 System and method for analyte measurement using dose sufficiency electrodes 1 2008
7,977,112 System and method for determining an abused sensor during analyte measurement 26 2008
7,879,618 Method and reagent for producing narrow, homogenous reagent strips 11 2009
7,892,849 Reagent stripe for test strip 18 2009
8,092,668 System and method for quality assurance of a biosensor test strip 0 2009
8,083,993 System and method for coding information on a biosensor test strip 3 2009
8,119,414 Test strip with slot vent opening 0 2010
8,142,721 Test strip with slot vent opening 0 2010
8,859,293 Method for determining whether a disposable, dry regent, electrochemical test strip is unsuitable for use 0 2011
8,211,379 Test strip with slot vent opening 1 2011
8,222,044 Test strip with flared sample receiving chamber 2 2011
9,017,543 Method for determining the concentration of an analyte in a liquid sample using small volume samples and fast test times 0 2013
9,017,544 Determining blood glucose in a small volume sample receiving cavity and in a short time period 0 2013
 
THERESENSE, INC. (1)
8,795,176 Integrated sample acquisition and analyte measurement device 0 2007
 
Elikan Technologies, Inc. (1)
7,297,151 Method and apparatus for body fluid sampling with improved sensing 141 2003
 
PEPEX BIOMEDICAL, LLC (2)
9,044,178 Electrochemical sensor and method for manufacturing 0 2008
8,506,740 Manufacturing electrochemical sensor module 2 2009
 
Pelikon Technologies, Inc. (1)
7,648,468 Method and apparatus for penetrating tissue 100 2002
 
Peliken Technologies, Inc. (1)
7,666,149 Cassette of lancet cartridges for sampling blood 25 2002
 
CORANGE INTERNATIONAL LIMITED (1)
* 2003/0116,447 Electrodes, methods, apparatuses comprising micro-electrode arrays 59 2002
 
Abbott Diabates Care Inc. (1)
8,557,104 In vitro analyte sensor, and methods 0 2012
 
ABBOTT LABORATORIES (4)
* 6,863,800 Electrochemical biosensor strip for analysis of liquid samples 178 2002
7,905,999 Biosensor strips and methods of preparing same 1 2005
* 2006/0278,525 Biosensor strips and methods of preparing same 9 2005
* 2007/0272,563 Biosensors and Methods of Preparing Same 2 2007
 
BOSTON SCIENTIFIC SCIMED, INC. (3)
8,455,088 Spun nanofiber, medical devices, and methods 0 2005
7,674,864 Polymeric hybrid precursors, polymeric hybrid precursor composite matrices, medical devices, and methods 1 2005
* 2007/0149,743 Polymeric hybrid precursors, polymeric hybrid precursor composite matrices, medical devices, and methods 1 2005
 
AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (1)
7,563,588 Electrically non-conductive, nanoparticulate membrane 9 2004
 
LIFESCAN, INC. (2)
7,050,843 Electrically-conductive patterns for monitoring the filling of medical devices 125 2004
7,548,772 Electrically-conductive patterns for monitoring the filling of medical devices 93 2006
 
INFOPIA CO., LTD. (2)
* 7,297,248 Glucose strip sensor and glucose measurement method using the glucose strip sensor 91 2001
* 2004/0146,958 Glucose strip sensor and glucose measurement using the glucose strip sensor 43 2003
 
PANASONIC HEALTHCARE HOLDINGS CO., LTD. (14)
7,022,218 Biosensor with interdigitated electrodes 113 2002
* 2004/0005,721 Biosensor 13 2003
9,046,479 Biosensor, method of producing the same and detection system comprising the same 0 2009
8,597,570 Measurement device, insulin infusion device, measurement method, method for controlling insulin infusion device, and program 16 2009
8,480,878 Biosensor, thin film electrode forming method, quantification apparatus, and quantification method 2 2011
8,480,866 Biosensor, thin film electrode forming method, quantification apparatus, and quantification method 2 2011
8,470,162 Biosensor, thin film electrode forming method, quantification apparatus, and quantification method 2 2011
* 2011/0147,234 Biosensor, thin film electrode forming method, quantification apparatus, and quantification method 9 2011
* 2011/0117,269 Biosensor, thin film electrode forming method, quantification apparatus, and quantification method 9 2011
8,480,867 Biosensor, thin film electrode forming method, quantification apparatus, and quantification method 2 2011
8,475,646 Biosensor, thin film electrode forming method, quantification apparatus, and quantification method 2 2011
8,349,157 Biosensor, thin film electrode forming method, quantification apparatus, and quantification method 7 2012
8,741,124 Biosensor, thin film electrode forming method, quantification apparatus, and quantification method 1 2013
8,980,074 Biosensor, thin film electrode forming method, quantification apparatus, and quantification method 0 2013
 
PEPEX BIOMEDICAL, INC. (2)
8,702,932 Electrochemical sensor and method for manufacturing 0 2008
8,951,377 Manufacturing electrochemical sensor module 0 2012
* Cited By Examiner