Camptothecin-taxoid conjugates as antimitotic and antitumor agents

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United States of America Patent

PATENT NO 6593334
SERIAL NO

10137166

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Abstract

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Compounds according to formula I: C'--L--T (I), wherein C' is a camptothecin group; L is a linking moiety; T is a taxoid group, pharmaceutically acceptable salt thereof. The compounds are useful in, among other things, treating cancer in subjects in need thereof, including cellular differentiation, and inhibiting cellular mitosis.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL THE300 BYNUM HALL CAMPUS BOX 4100 CHAPEL HILL NC 27599 UNITED STATES OF AMERICA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bastow, Kenneth F Chapel Hill, NC 19 111
Lee, Fang-Yu Taichung, TW 33 261
Lee, Kuo-Hsiung Chapel Hill, NC 71 461
Nakanishi, Yuka Chapel Hill, NC 1 5
Ohtsu, Hironari Chapel Hill, NC 2 29

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