Antibiotic calcium phosphate coating
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United States of America Patent
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Jul 22, 2003
Grant Date -
Apr 24, 2003
app pub date -
Oct 24, 2001
filing date -
Oct 24, 2001
priority date (Note) -
Expired
status (Latency Note)
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Abstract
A process for applying a coating having a therapeutic agent such as an antibiotic to an implant uses the high surface area of a calcium phosphate coated metal implant as a repository for the therapeutic agent. The implant is coated with one or more layers of calcium phosphate minerals such as hydroxyapatite. After the crystalline layer is applied, which is usually done within an aqueous solution, the implant is dried and packaged. Immediately prior to implantation, the implant is removed from the package and the crystalline layer of calcium phosphate is wetted with an aqueous solution containing the therapeutic agent.
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