Osmotic device containing alprazolam and an antipsychotic agent
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United States of America Patent
Stats
-
Jul 29, 2003
Grant Date -
May 2, 2002
app pub date -
Jan 8, 2001
filing date -
Jan 13, 2000
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
The present invention provides an osmotic device containing controlled release alprazolam in the core optionally in combination with an anti-psychotic agent, in a rapid release external coat. A wide range of anti-psychotic agents can be used in this device. Particular embodiments of the invention provide osmotic devices having predetermined release profiles. One preferred embodiment of the osmotic device includes an external coat that has been spray coated rather compression coated onto the device. The device with spray coated external core is smaller and easier to swallow than the similar device having a compression coated external coat. The device is useful for the treatment of depression, anxiety or psychosis related disorders.
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