Bactericidal/permeability-increasing protein (BPI) deletion analogs
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United States of America Patent
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Jul 29, 2003
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N/A
app pub date -
May 25, 2000
filing date -
Jun 19, 1998
priority date (Note) -
Expired
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Abstract
Novel BPI deletion analogs are provided that consist of amino acid residues 10 through 193 of mature human BPI wherein the cysteine residue at BPI amino acid position 132 is replaced by another amino acid. Fusion proteins comprising these analogs are also provided, as are polynucleotides encoding these products, materials and methods for their recombinant production, compositions and medicaments of these products, and therapeutic uses for these products.
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