Moraxella catarrhalis BASB034 polypeptides and uses thereof
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United States of America Patent
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Jul 29, 2003
Grant Date -
N/A
app pub date -
May 14, 2001
filing date -
Sep 14, 1998
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Provided are Moraxella catarrhalis BASB034 polypeptides and immnunogenic fragments of BASB034 polypeptides Preferably, the immunogenic fragments have at least 15 amino acids that match an aligned contiguous segment of SEQ ID NOs:2, 4, 6 or 8. The immunogenic fragments, when administered to a subject in a suitable composition (which can include an adjuvant, or a suitable carrier coupled to the fragment) raise an immune response that recognizes a polypeptide having the sequence of SEQ ID NOs:2, 4, 6 or 8. The invention further provides immunogenic compositions containing BASB034 polypeptides and immunogenic fragments thereof, and a pharmaceutically acceptable carrier. Also provided are fusion proteins that contain BASB034 polypeptides and immunogenic fragments thereof.
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