Glycosylation engineering of antibodies for improving antibody-dependent cellular cytotoxicity
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United States of America Patent
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Aug 5, 2003
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N/A
app pub date -
Apr 20, 1999
filing date -
Apr 20, 1998
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Abstract
The present invention relates to the field glycosylation engineering of proteins. More particular, the present invention is directed to the glycosylation engineering of proteins to provide proteins with improved therapeutic properties, e.g., antibodies, antibody fragments, or a fusion protein that includes a region equivalent to the Fc region of an immunoglobulin, with enhanced Fc-mediated cellular cytotoxicity.
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