Synthesis of epothilones, intermediates thereto and analogues thereof

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United States of America Patent

PATENT NO 6603023
SERIAL NO

10062376

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Abstract

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The present invention provides convergent processes for preparing epothilone A and B, desoxyepothilones A and B, and analogues thereof, useful in the treatment of cancer and cancer which has developed a multidrug-resistant phenotype. Also provided are intermediates useful for preparing said epothilones.

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Patent Owner(s)

Patent OwnerAddress
SLOAN KETTERING INSTITUTE FOR CANCER RESEARCH1275 YORK AVENUE NEW YORK NY 10021

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Balog, Aaron New York, NY 22 334
Bertinato, Peter Old Lyme, CT 37 497
Bertino, Joseph R Branford, CT 29 195
Chou, Ting-Chao Paramus, NJ 51 425
Danishefsky, Samuel J Englewood, NJ 112 1071
Harris, Christina New York, NY 6 99
Kamenecka, Ted New Brunswick, NJ 22 334
Kuduk, Scott Harleysville, PA 44 511
Meng, DongFang New York, NY 31 198
Savin, Kenneth A Indianapolis, IN 23 339
Sorensen, Erik J San Diego, CA 25 387
Su, Dai-Shi Ambler, PA 43 418
Zhang, Xiu-Guo New York, NY 4 95

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