Methods of using in situ hydration of hydrogel articles for sealing or augmentation of tissue or vessels
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United States of America Patent
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Aug 12, 2003
Grant Date -
Nov 29, 2001
app pub date -
Aug 14, 1998
filing date -
Aug 14, 1998
priority date (Note) -
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Abstract
Pharmaceutically acceptable hydrogel polymers of natural, recombinant or synthetic origin, or hybrids thereof, are introduced in a dry, less hydrated, or substantially deswollen state and rehydrate in a physiological environment to undergo a volumetric expansion and to affect sealing, plugging, or augmentation of tissue, defects in tissue, or of organs. The hydrogel polymers may deliver therapeutic entities by controlled release at the site. Methods to form useful devices from such polymers, and to implant the devices are provided.
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