Mitochondrial dosimeter
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United States of America Patent
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Aug 12, 2003
Grant Date -
N/A
app pub date -
Mar 15, 2000
filing date -
Aug 20, 1998
priority date (Note) -
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Abstract
Mitochondrial mutations occur as a product of contact of a person with an environmental pollutant. Mitochondrial mutations are readily detectable in body fluids. Measurement of mitochondrial mutations in body fluids can be used as a dosimeter to monitor exposure to the environmental pollutant. Mitochondrial mutations can also be detected in cancer patients. Probes and primers containing mutant mitochondrial sequences can be used to monitor patient condition.
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