Tyrosine derivatives with anti-leukotrienen activity

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 6605722
APP PUB NO 20030087910A1
SERIAL NO

10203424

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Compounds which can be represented by general formula (I) indicated below and in which: ##STR1## R.sub.1 and R.sub.2 are selected, independently, from hydrogen, an alkyl group having from 1 to 4 carbon atoms, a halogen group such as a fluoro, chloro or bromo group, the methoxy group, the cyano group, or the trifluoromethyl group, and R.sub.3 is selected, independently, from a phenyl or a 2 (or 3 or 4)-pyridyl group, unsubstituted or mono- or di-substituted with an alkyl or alkoxy group having from 1 to 4 carbon atoms, with a halogen group such as a fluoro or chloro group, with the trifluoromethyl group, with the cyano group, with the nitro group, with the amino group, or with the phenyl group, a 1 (or 2)-naphthyl group, a 2 (or 3)-indolyl group as such or N-alkylated with an alkyl group having from 1 to 3 carbon atoms, a 2 (or 3, 4, 5, 6, 7 or 8)-quinolinyl or a 1 (or 3, 4, 5, 6, 7 or 8)-isoquinolinyl group, unsubstituted or mono- or di-substituted with a group selected, independently, from the methyl, ethyl, propyl, isopropyl, methoxy, fluoro, chloro, trifluoromethyl, cyano, amino, or nitro groups, a 2 (or 5 or 6)-quinoxalyl group, a (or 4, 5, 6, 7 or 8) cinnolyl group, or a 2 (or 4, 5, 6 or 7)-benzimidazolyl group, and in which the configuration of the chiral centre marked with an asterisk (*) in the general formula (I) may be, independently, L, D or DL (racemic).

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Patent Owner(s)

Patent OwnerAddress
ROTTAPHARM BIOTECH S R L20900 MONZA

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Makovec, Francesco Monza, IT 56 282
Peris, Walter Milan, IT 16 62
Rovati, Lucio Claudio Monza, IT 51 122

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