Antisense inhibition of E2A-Pbx1 expression
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United States of America Patent
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Aug 19, 2003
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N/A
app pub date -
Jul 25, 2000
filing date -
Sep 30, 1999
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Abstract
Compounds, compositions and methods are provided for inhibiting E2A-Pbx1 mediated transformation. The compositions comprise antisense compounds targeted to nucleic acids encoding E2A-Pbx1. Methods of using these antisense compounds for inhibition of E2A-Pbx1 expression and for treatment of diseases, particularly cancers, associated with overexpression or constitutive activation of E2A-Pbx1 are provided.
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