Screening compounds for the ability to alter the production of amyloid-.beta. peptide

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United States of America Patent

PATENT NO 6610493
SERIAL NO

08665649

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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This invention provides methods of screening compounds for their ability to alter the production of A.beta.(x.gtoreq.41) alone or in combination with A.beta.(x.ltoreq.40). The methods involve administering compounds to cells, specifically measuring the amounts of A.beta.(x.ltoreq.40) and A.beta.(x.gtoreq.41) produced by the cells, and comparing these amounts to that produced by the cells without administration of the compounds.

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Patent Owner(s)

  • THE BRIGHAM AND WOMEN'S HOSPITAL, INC.;ELAN PHARMACEUTICALS, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Citron, Martin Thousands Oaks, CA 6 80
Schenk, Dale Burlingame, CA 2 55
Selkoe, Dennis J Jamaica Plain, MA 12 504
Seubert, Peter A San Francisco, CA 33 1389

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