Method of producing tiazofurin and other C-nucleosides

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United States of America Patent

PATENT NO 6613896
SERIAL NO

09445713

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Abstract

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C-nucleosides are synthesized by a method in which a sugar is derivatized in a single step to provide a heterocycle at the C.sub.1 position, and then the heterocycle is aromatized in another single step. In one class of preferred embodiments a cyano sugar is converted into thiocarboxamide, and subsequently condensed to form an azole ring. In a second class of preferred embodiments a cyano sugar is condensed with an amino acid to provide the azole ring. In a third class of preferred embodiments a halo sugar is condensed with a preformed heterocycle to provide the azole ring.

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Patent Owner(s)

Patent OwnerAddress
ICN PHARMACEUTICALS INC3300 HYLAND AVENUE COSTA MESA CA 92626 UNITED STATES OF AMERICA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Averett, Devron Irvine, CA 11 559
Bandaru, Rajanikanth Irvine, CA 4 45
Ramasamy, Kandasamy Laguna Hills, CA 13 528

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