Electrochemical coagulation assay and device
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United States of America Patent
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Sep 16, 2003
Grant Date -
N/A
app pub date -
Dec 13, 2000
filing date -
Dec 13, 2000
priority date (Note) -
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Abstract
Methods and devices for electrochemically detecting a change in the viscosity of a fluid are provided. In the subject methods, a fluid sample is introduced into an electrochemical cell having oppositely spaced apart working and reference electrodes. An electric potential is applied to the cell to first achieve a steady state cell current. A decrease in the steady state cell current is then detected and related to a change in viscosity of the sample. In many embodiments, the sample is blood and the change in viscosity is related to the onset of coagulation in the blood sample, and often the PT of the blood sample. Also provided are test strips, kits thereof and meters for use in practicing the subject methods.
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