US Patent No: 6,620,627
Number of patents in Portfolio can not be more than 2000
Increased separation efficiency via controlled aggregation of magnetic nanoparticles
Stats
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Sep 16, 2003
Issued date -
Oct 31, 2000
filing date -
09/702,188
serial no -
In Force
status
Importance
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Abstract
Compositions and methods are disclosed which enhance the microscopic observation and analysis of biological entities such as cells, bacteria and viruses by eliminating interfering magnetic clusters created by naturally occurring aggregators of colloidal magnetic particles. Additionally means for significantly enhancing the magnetic isolation of low antigen density target cells from biological samples are disclosed.
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First Claim
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International Classification(s)
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- [Patents Count]
Cited Art
| Patent Info | (Count) | # Cites | Year |
|---|---|---|---|
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| 5,200,084 Apparatus and methods for magnetic separation | 111 | 1990 | |
| 5,186,827 Apparatus for magnetic separation featuring external magnetic means | 114 | 1991 | |
| 5,466,574 Apparatus and methods for magnetic separation featuring external magnetic means | 142 | 1993 | |
| 5,622,831 Methods and devices for manipulation of magnetically collected material | 32 | 1995 | |
| 5,698,271 Methods for the manufacture of magnetically responsive particles | 79 | 1995 | |
| 6,013,188 Methods for biological substance analysis employing internal magnetic gradients separation and an externally-applied transport force | 43 | 1997 | |
| 5,876,593 Magnetic immobilization and manipulation of biological entities | 19 | 1997 | |
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| 4,812,401 Reversible agglutination mediators for separating cells from whole blood | 7 | 1987 | |
| 5,405,743 Reversible agglutination mediators | 6 | 1994 | |
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| 4,868,130 Methods for conducting specific binding assays | 33 | 1987 | |
| 6,121,055 Methods and devices for conducting specific binding assays | 9 | 1995 | |
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| 6,207,380 Reagents and methods useful for detecting diseases of the urinary tract | 11 | 1998 | |
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| 6,146,838 Detecting water-borne parasites using electrochemiluminescence | 11 | 1997 | |
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| 6,004,743 Method and apparatus for bulk enrichment of a population or subpopulation of cells | 4 | 1997 | |
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| 4,973,669 Monoclonal IgM antibody with specificity against hepatitis B surface antigen | 2 | 1988 | |
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| 5,779,892 Magnetic separator with magnetic compensated release mechanism for separating biological material | 11 | 1996 | |
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| 5,635,356 Anti-oncoimmunin-M antibodies and uses thereof | 3 | 1994 | |
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| 6,117,985 Antibody compositions for preparing enriched cell preparations | 35 | 1998 | |
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| 4,253,844 Insolubilized proteins and immunoassays utilizing them | 21 | 1979 | |
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| 5,665,582 Isolation of biological materials | 101 | 1994 | |
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| 5,439,586 Magnetic filter with ordered wire array | 13 | 1993 | |
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| 6,150,181 Magnetic nanoparticles coupled to annexine, and utilization thereof | 6 | 1998 | |
Patent Citation Ranking
Maintenance Fees
| Fee | Large entity fee | small entity fee | micro entity fee | due date |
|---|---|---|---|---|
| 11.5 Year Payment | $7400.00 | $3700.00 | $1850.00 | Mar 16, 2015 |
| Fee | Large entity fee | small entity fee | micro entity fee |
|---|---|---|---|
| Surcharge - 11.5 year - Late payment within 6 months | $160.00 | $80.00 | $40.00 |
| Surcharge after expiration - Late payment is unavoidable | $700.00 | $350.00 | $175.00 |
| Surcharge after expiration - Late payment is unintentional | $1,640.00 | $820.00 | $410.00 |