Thyroid receptor ligands
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United States of America Patent
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Sep 16, 2003
Grant Date -
Dec 13, 2001
app pub date -
Apr 17, 2001
filing date -
Apr 21, 2000
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The invention provides thiazolidinedione, oxadiazolidinedione, and triazolone compounds of Formula (I) which compounds are thyroid receptor ligands. ##STR1## The invention further provides pharmaceutical compositions and kits comprising such compounds and methods of treating obesity, overweight condition, hyperlipidemia, glaucoma, cardiac arrhythmias, skin disorders, thyroid disease, hypothyroidism, thyroid cancer, diabetes, atherosclerosis, hypertension, coronary heart disease, congestive heart failure, hypercholesterolemia, depression, and osteoporosis using such compounds.
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