Cellular matrix

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 6623963
SERIAL NO

09467584

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A biocompatible, resorbable Type II collagen-based matrix is reconstituted from solubilized animal cartilage tissue and used in the culture and growth of cells, such as chondrocyte cells. The matrix is produced by isolating cartilage tissue, solubilizing and reconstituting the cartilage to form a fleece-like material, pressing the fleece-like material to form a sheet-like article, and sterilizing the article. An implantable article for cartilage repair includes chondrocyte cells retained on the matrix.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
VERICEL CORPORATIONCAMBRIDGE, MA20
Behrens, Peter51377 LEVERKUSEN1
Muller, Peter Karl51377 LEVERKUSEN1
Rohwedel, Jurgen51377 LEVERKUSEN1
Russlies, Martin51377 LEVERKUSEN1

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Behrens, Peter Aegidiensir 51, 23552 Lubeck, DE 5 174
Giannetti, Bruno Bonn, DE 17 530
Muller, Peter Karl Auf dem Vorbeck 25, 29562 Lubeck, DE 1 35
Rohwedel, Jurgen Huexatr 112-116, 23552 Lubeck, DE 2 35
Russlies, Martin Gustav-Falke-Sir 16B, 23562 Lubeck, DE 2 36

Cited Art Landscape

Patent Info (Count) # Cites Year
 
REGEN BIOLOGICS, INC. (1)
5735902 Hand implant device 8 1996
 
COLLAGEN AESTHETICS, INC. (2)
4424208 Collagen implant material and method for augmenting soft tissue 300 1982
4488911 Non-antigenic collagen and articles of manufacture 123 1983
 
SMITH & NEPHEW, INC. (2)
5902741 Three-dimensional cartilage cultures 186 1995
5842477 Method for repairing cartilage 463 1996
 
OSTEOMEDICAL LIMITED (1)
4882149 Pharmaceutical depot preparation 57 1988
 
COHESION TECHNOLOGIES, INC. (2)
4582640 Injectable cross-linked collagen implant material 300 1984
4642117 Mechanically sheared collagen implant material and method 182 1985
 
GEISTLICH PHARMA AG (1)
5837278 Resorbable collagen membrane for use in guided tissue regeneration 62 1996
 
Colla-Tec, Incorporated (1)
5206028 Dense collagen membrane matrices for medical uses 153 1991
 
ED. GEISTLICH SOHNE AG FUR CHEMISCHE INDUSTRIE (1)
5076265 Hydrogel sheet wound dressings 28 1989
 
ReGen Corporation (3)
5116374 Prosthetic meniscus 82 1990
5158574 Prosthetic meniscus 78 1991
5258043 Method for making a prosthetic intervertebral disc 241 1991
 
GENSCI ORTHOBIOLOGICS, INC. (2)
4394370 Bone graft material for osseous defects and method of making same 410 1981
4472840 Method of inducing osseous formation by implanting bone graft material 273 1982
 
IVY SPORTS MEDICINE, LLC (1)
5677284 Charged collagen particle-based delivery matrix 21 1995
 
SOCIETE ANONYME DE DEVELOPMENT DES UTILISATIONS DU CUIR-SADUC (3)
4931546 Process for the treatment of collagen, notably for facilitating its cross-linking, and the collagen obtained by the application of the said process 41 1987
5201745 Visceral surgery patch 93 1991
5618551 Biocompatible bioresorbable and non-toxic adhesive composition for surgical use 67 1995
* Cited By Examiner

Patent Citation Ranking

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Patent Info (Count) # Cites Year
 
MITSUO OCHI (1)
* 2007/0172,812 Tissue equivalent for transplantation and method for producing same 4 2007
 
Other [Check patent profile for assignment information] (3)
* 2006/0111,778 Methods of promoting healing of cartilage defects and method of causing stem cells to differentiate by the articular chondrocyte pathway 21 2005
8377432 Method and composition for neochondrogenesis 0 2010
* 2011/0052,526 METHOD AND COMPOSITION FOR NEOCHONDROGENESIS 0 2010
 
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (1)
* 2006/0172,412 Support device for cells culture 14 2005
 
VERIGEN AG (2)
* 2004/0136,968 Autologous cells on a support matrix for tissue repair 24 2003
* 2006/0159,665 Seed tear resistant scaffold 1 2005
 
TAIPEI MEDICAL UNIVERSITY (2)
8431399 Method to restore cartilaginous phenotype of chondrocytes after cultured and expanded in vitro 0 2010
* 2011/0217,773 METHOD TO RESTORE CARTILAGINOUS PHENOTYPE OF CHONDROCYTES AFTER CULTURED AND EXPANDED IN VITRO 0 2010
 
ZIMMER, INC. (2)
9289302 Mosaicplasty constructs 0 2009
* 2010/0161,073 MOSAICPLASTY CONSTRUCTS 2 2009
 
PHILLIPS, FRANK M. (1)
8697139 Method of intervertebral disc treatment using articular chondrocyte cells 0 2004
 
GENZYME CORPORATION (1)
* 2011/0262,516 AUTOLOGOUS CELLS ON A SUPPORT MATRIX FOR TISSUE REPAIR 0 2011
 
Phillips Plastics Corporation (2)
8062655 Composite scaffold structure 1 2007
* 2009/0062,821 COMPOSITE SCAFFOLD STRUCTURE 1 2007
 
PENTAX CORPORATION (1)
* 2006/0212,125 Bone repairing material using a chondrocyte having the potential for hypertrophy and a scaffold 2 2006
 
SYNOVIS ORTHOPEDIC AND WOUNDCARE, INC. (6)
* 2007/0218,038 STABILIZED, STERILIZED COLLAGEN SCAFFOLDS WITH ACTIVE ADJUNCTS ATTACHED 2 2007
* 2009/0018,655 Composite Implant for Surgical Repair 86 2007
* 9387280 Device for soft tissue repair or replacement 0 2008
* 2010/0063,599 DEVICE FOR SOFT TISSUE REPAIR OR REPLACEMENT 4 2008
9694037 Stabilized, sterilized collagen scaffolds with active adjuncts attached 0 2009
* 2009/0196,898 STABILIZED, STERILIZED COLLAGEN SCAFFOLDS WITH ACTIVE ADJUNCTS ATTACHED 0 2009
 
HOWMEDICA OSTEONICS CORP. (1)
* 2007/0299,517 Articular cartilage implant 27 2006
 
Taipei Biotechnology Ltd., Inc. (2)
* 6852331 Fabrication of a cartilage implant 12 2002
* 2003/0152,556 Fabrication of a cartilage implant 2 2002
 
HISTOGENICS CORPORATION (1)
9701940 Cell-support matrix having narrowly defined uniformly vertically and non-randomly organized porosity and pore density and a method for preparation thereof 0 2014
 
PFIZER INC. (1)
* 2003/0191,107 3-(Imidazolyl)-2-aminopropanoic acids 3 2003
 
SHIMIZU, YASUHIKO (2)
* 7011829 Tissue filler 1 2001
* 2004/0028,659 Tissue filler 0 2003
 
SOFRADIM PRODUCTION (7)
9308068 Implant for parastomal hernia 0 2008
9242026 Biosynthetic implant for soft tissue repair 1 2009
9554887 Prosthesis comprising a three-dimensional and openworked knit 0 2012
9622843 Umbilical hernia prosthesis 0 2012
9526603 Reversible stiffening of light weight mesh 0 2012
9445883 Barbed prosthetic knit and hernia repair mesh made therefrom as well as process for making said prosthetic knit 0 2012
9499927 Method for producing a prosthesis for reinforcing the abdominal wall 0 2013
 
ZIMMER ORTHOBIOLOGICS, INC. (4)
8173162 Preparation for repairing cartilage tissue, especially articular cartilage defects 4 2004
* 2007/0148,242 Preparation for repairing cartilage tissue, especially articular cartilage defects 15 2004
8945535 Implant for the repair of a cartilage defect and method for manufacturing the implant 6 2006
* 2008/0269,895 Implant for the Repair of a Cartilage Defect and Method for Manufacturing the Implant 7 2006
 
WARSAW ORTHOPEDIC, INC. (8)
* 2004/0054,414 Collagen-based materials and methods for augmenting intervertebral discs 73 2002
7744651 Compositions and methods for treating intervertebral discs with collagen-based materials 2 2005
7713303 Collagen-based materials and methods for augmenting intervertebral discs 4 2005
8399619 Injectable collagen material 0 2006
8118779 Collagen delivery device 0 2006
7731981 Collagen-based materials and methods for treating synovial joints 2 2007
* 9649341 Collagen matrix for tissue engineering 0 2011
* 2012/0276,202 COLLAGEN MATRIX FOR TISSUE ENGINEERING 1 2011
 
MUSCULOSKELETAL TRANSPLANT FOUNDATION (10)
7901457 Cartilage allograft plug 39 2003
7488348 Cartilage allograft plug 35 2005
7815926 Implant for articular cartilage repair 11 2006
7837740 Two piece cancellous construct for cartilage repair 31 2007
RE42208 Glue for cartilage repair 21 2008
8221500 Cartilage allograft plug 9 2008
8435551 Cancellous construct with support ring for repair of osteochondral defects 5 2009
8906110 Two piece cancellous construct for cartilage repair 0 2010
RE43258 Glue for cartilage repair 6 2010
8292968 Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles 10 2011
* Cited By Examiner