US Patent No: 6,623,963

Number of patents in Portfolio can not be more than 2000

Cellular matrix

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Importance

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Abstract

A biocompatible, resorbable Type II collagen-based matrix is reconstituted from solubilized animal cartilage tissue and used in the culture and growth of cells, such as chondrocyte cells. The matrix is produced by isolating cartilage tissue, solubilizing and reconstituting the cartilage to form a fleece-like material, pressing the fleece-like material to form a sheet-like article, and sterilizing the article. An implantable article for cartilage repair includes chondrocyte cells retained on the matrix.

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First Claim

Related Publications

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Patent Owner(s)

Patent OwnerAddressTotal Patents
VERIGEN AG51377 LEVERKUSEN15
BEHRENS, PETER51377 LEVERKUSEN1
MULLER, PETER KARL51377 LEVERKUSEN1
ROHWEDEL, JURGEN51377 LEVERKUSEN1
RUSSLIES, MARTIN51377 LEVERKUSEN1

International Classification(s)

  • [Classification Symbol]
  • [Patents Count]

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Behrens, Peter Lubeck, DE 4 47
Giannetti, Bruno Bonn, DE 16 150
Muller, Peter Karl Auf dem Vorbeck 25, 29562 Lubeck, DE 1 20
Rohwedel, Jurgen Huexatr 112-116, 23552 Lubeck, DE 2 20
Russlies, Martin Gustav-Falke-Sir 16B, 23562 Lubeck, DE 2 20

Cited Art

Patent Info (Count) # Cites Year
 
REGEN CORPORATION (3)
5,116,374 Prosthetic meniscus 60 1990
5,158,574 Prosthetic meniscus 63 1991
5,258,043 Method for making a prosthetic intervertebral disc 196 1991
 
SOCIETE ANONYME DE DEVELOPMENT DES UTILISATIONS DU CUIR-SADUC (3)
4,931,546 Process for the treatment of collagen, notably for facilitating its cross-linking, and the collagen obtained by the application of the said process 22 1987
5,201,745 Visceral surgery patch 77 1991
5,618,551 Biocompatible bioresorbable and non-toxic adhesive composition for surgical use 28 1995
 
COHESION TECHNOLOGIES, INC. (2)
4,582,640 Injectable cross-linked collagen implant material 182 1984
4,642,117 Mechanically sheared collagen implant material and method 130 1985
 
COLLAGEN AESTHETICS, INC. (2)
4,424,208 Collagen implant material and method for augmenting soft tissue 192 1982
4,488,911 Non-antigenic collagen and articles of manufacture 113 1983
 
GENSCI ORTHOBIOLOGICS, INC. (2)
4,394,370 Bone graft material for osseous defects and method of making same 272 1981
4,472,840 Method of inducing osseous formation by implanting bone graft material 204 1982
 
SMITH & NEPHEW, INC. (2)
5,902,741 Three-dimensional cartilage cultures 104 1995
5,842,477 Method for repairing cartilage 225 1996
 
COLLA-TEC, INC., A CORP. OF DE. (1)
5,206,028 Dense collagen membrane matrices for medical uses 94 1991
 
ED. GEISTLICH SOEHNE AG FUER CHEMISCHE INDUSTRIE (1)
5,076,265 Hydrogel sheet wound dressings 17 1989
 
GEISTLICH PHARMA AG (1)
5,837,278 Resorbable collagen membrane for use in guided tissue regeneration 37 1996
 
IVY SPORTS MEDICINE, LLC (1)
5,677,284 Charged collagen particle-based delivery matrix 13 1995
 
OSTEOMEDICAL LIMITED (1)
4,882,149 Pharmaceutical depot preparation 38 1988
 
REGEN BIOLOGICS, INC. (1)
5,735,902 Hand implant device 7 1996

Patent Citation Ranking

Forward Cites

Patent Info (Count) # Cites Year
 
MUSCULOSKELETAL TRANSPLANT FOUNDATION (9)
7,901,457 Cartilage allograft plug 6 2003
7,488,348 Cartilage allograft plug 8 2005
7,815,926 Implant for articular cartilage repair 2 2006
7,837,740 Two piece cancellous construct for cartilage repair 4 2007
RE42208 Glue for cartilage repair 3 2008
8,221,500 Cartilage allograft plug 0 2008
8,435,551 Cancellous construct with support ring for repair of osteochondral defects 0 2009
RE43258 Glue for cartilage repair 0 2010
8,292,968 Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles 0 2011
 
WARSAW ORTHOPEDIC, INC. (5)
7,744,651 Compositions and methods for treating intervertebral discs with collagen-based materials 1 2005
7,713,303 Collagen-based materials and methods for augmenting intervertebral discs 2 2005
8,399,619 Injectable collagen material 0 2006
8,118,779 Collagen delivery device 0 2006
7,731,981 Collagen-based materials and methods for treating synovial joints 0 2007
 
PHILLIPS PLASTICS CORPORATION (1)
8,062,655 Composite scaffold structure 0 2007
 
SHIMIZU, YASUHIKO (1)
7,011,829 Tissue filler 1 2001
 
TAIPEI BIOTECHNOLOGY LTD., INC. (1)
6,852,331 Fabrication of a cartilage implant 10 2002
 
TAIPEI MEDICAL UNIVERSITY (1)
8,431,399 Method to restore cartilaginous phenotype of chondrocytes after cultured and expanded in vitro 0 2010
 
ZIMMER ORTHOBIOLOGICS, INC. (1)
8,173,162 Preparation for repairing cartilage tissue, especially articular cartilage defects 0 2004
 
OTHER [CHECK PATENT PROFILE FOR ASSIGNMENT INFORMATION] (1)
8,377,432 Method and composition for neochondrogenesis 0 2010

Maintenance Fees

Fee Large entity fee small entity fee micro entity fee due date
11.5 Year Payment $7400.00 $3700.00 $1850.00 Mar 23, 2015
Fee Large entity fee small entity fee micro entity fee
Surcharge - 11.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge after expiration - Late payment is unavoidable $700.00 $350.00 $175.00
Surcharge after expiration - Late payment is unintentional $1,640.00 $820.00 $410.00