Proteoglycan compositions for treatment of cardiovascular inflammatory diseases

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United States of America Patent

PATENT NO 6624148
APP PUB NO 20030104088A1
SERIAL NO

10329367

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Compositions with synergistic anti-inflammatory effects in inflammatory diseases resulting from activation and consequent degranulation of mast cells and followed by secretion of inflammatory biomolecules from the activated mast cells, composed of a heavily sulfated, non-bovine proteoglycan such as shark cartilage chondroitin sulfate C, and one or more of a hexosamine sulfate such as D-glucosamine sulfate, a flavone such as quercetin, an unrefined olive kernel extract that increases absorption of these compositions in various routes of administration, S-adenosylmethionine, a histamine-1 receptor antagonist, a histamine-3 receptor agonist, an antagonist of the actions of CRH, caffeine, and a polyamine.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Theoharides, Theoharis C 14 Parkman St., Brookline, MA 02446 35 444

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