Method of preventing abuse of opioid dosage forms
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United States of America Patent
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Sep 30, 2003
Grant Date -
Jan 10, 2002
app pub date -
Mar 22, 2001
filing date -
Dec 22, 1997
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The invention relates in part to a method of reducing the abuse potential of an oral dosage form of an opioid analgesic, wherein an analgesically effective amount of an orally active opioid agonist is combined with an opioid antagonist into an oral dosage form which would require at least a two-step extraction process to be separated from the opioid agonist, the amount of opioid antagonist including being sufficient to counteract opioid effects if extracted together with the opioid agonist and administered parenterally.
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