Benzimidazolone peptidometics as thrombin receptor antagonist

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United States of America Patent

PATENT NO 6630451
SERIAL NO

09599826

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Abstract

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The invention is directed to novel benzimidazolone peptidomimetic compounds which are useful as thrombin receptor antagonists for the treatment of diseases associated with thrombosis, restenosis, hypertension, heart failure, arrhythmia, inflammation, angina, stroke, atherosclerosis, ischemic conditions, Angiogenesis related disorders, cancer, and neurodegenerative disorders. Pharmaceutical compositions comprising the substituted benzimidazolone peptidomimetics of the present invention and methods of treating conditions mediated by the thrombin receptor are also disclosed.

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Patent Owner(s)

Patent OwnerAddress
COR THERAPEUTICS INC256 EAST GRAND AVENUE SAN FRANCISCO CA 94080
ORTHO-MENEIL PHARMACEUTICAL INCP O BOX 300 920 U S ROUTE #202 RARITAN NJ 08869

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Maryanoff, Bruce E Forest Grove, PA 104 912
McComsey, David F Warminster, PA 37 187
White, Kimberly B North Wales, PA 3 15
Zhang, Han-Cheng Lansdale, PA 37 208

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