Chlamydial vaccines and immunogenic compositions containing an outer membrane antigen and methods of preparation thereof
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United States of America Patent
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Oct 21, 2003
Issued Date -
N/A
app pub date -
May 28, 1999
filing date -
Sep 12, 1996
priority date (Note) -
Expired
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Abstract
Immunogenic compositions including vaccines are described that comprise an outer membrane antigen extract of a strain of Chlamydia and are effective in protection against disease caused by Chlamydia infection The immunogenic compositions may comprise the major outer membrane protein (MOMP) of Chlamydia which may be in a homooligomeric form or complexed with at least one other antigen of Chlamydia. The immunogenic composition may include an immunostimulating complex (ISCOM) and the outer membrane antigen may be incorporated therein. The immunogenic compositions have utility as chlamydial vaccines and in diagnostic applications.
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