Importance

Loading Importance Indicators...

Abstract

Methods for treating hair loss using a composition including a compound having the following structure ##STR1## and pharmaceutically acceptable salts, hydrates, and biohydrolyzable amides, esters, and imides thereof are provided. R.sub.1 is --(CH.sub.2).sub.n (CHNR.sub.7 R.sub.8).sub.m C(O)R.sub.9, wherein n is an integer from 1 to 3, and m is an integer from 0 to 1. R.sub.3 and R.sub.5 each, independently, is chlorine, bromine, iodine and --CH.sub.3. R.sub.7 and R.sub.8 each, independently, is hydrogen or C1 to C4 alkyl. R.sub.9 is hydroxy, C1 to C4 alkoxy and --NR.sub.7 R.sub.8. R.sub.31 is a hydrogen, chlorine, bromine, iodine, C1 to C4 alkyl, C4 to C6 cycloalklyl, C1 to C4 haloalkyl, C4 to C6 halocycloalkyl, or CH(R.sub.10)Ar. Ar is 5-hydroxypyrid-2-yl, 6-hydroxypyrid-3-yl, 6-hydroxypyridazin-3-yl, 6-methioxypyridazin-3-yl N-oxide or 6-hydroxypyridazin-3-yl N-oxide. R.sub.10 is hydrogen or C1 to C4 alkyl. R.sub.41 is hydroxy or C1 to C4 alkoxy.

Loading the Abstract Image...

First Claim