System and method for encapsulating biological material by applying electrostatic charge to capsules
Number of patents in Portfolio can not be more than 2000
United States of America Patent
Stats
-
Nov 18, 2003
Grant Date -
Feb 21, 2002
app pub date -
Jul 5, 2001
filing date -
Jul 5, 2000
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
A method and system for the effective and consistent encapsulation of viable (i.e., living or physiologically active) biological material (preferably, pancreatic islets also known as islets of Langerhans) with a polymeric material (preferably, a biocompatible semipermeable alginate) to form a gelled capsule, which preferably can be transplanted into genetically dissimilar hosts. The method includes an electrostatic mixing process for producing encapsulated cell clusters with at least two polymeric coatings, and the system includes an improved spinning disk atomizer. In an embodiment, biological material is encapsulated in a first alginate layer, the resultant capsules are suspended in a liquid carrier medium such as a saline solution, an electrostatic charge is applied to the carrier medium which is then introduced into an alginate solution, and the resultant suspension is atomized and gelled to form a second alginate layer.
First Claim
Family
International Classification(s)
- [Classification Symbol]
- [Patents Count]
Cited Art Landscape
Patent Citation Ranking
Advertisement
Advertisement
Advertisement
Recipient Email Address
Recipient Email Address
Comment
Recipient Email Address
Add to Portfolio(s)
To add this patent to one, or more, of your portfolios, simply click the add button.
This Patent is in these Portfolios:
Add to additional portfolios:
Last Refreshed On:
Changes done successfully