Method of treating colonic adenomas

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United States of America Patent

PATENT NO 6649649
SERIAL NO

09261034

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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This invention is directed to a method of retarding or preventing the transformation of a colonic adenoma to a colonic adenocarcinoma comprising the administration to a patient with FAP or a patient with one or more of said adenomas a non-toxic therapeutically effective amount of NSAID, said amount effective to inhibit the PGHS-2 in said adenoma. The preferred method comprises the administration of a specific PGHS-2 inhibiting agent as defined herein.

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Patent Owner(s)

Patent OwnerAddress
MERCK SHARP & DOHME CORP126 EAST LINCOLN AVENUE RAHWAY NJ 07065

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Evans, Jilly Brossard, CA 5 17
Kargman, Stacia Hampstead, CA 6 25
Simon, Thomas J Berwyn, PA 5 17

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