Polymeric foam reservoirs for an electrotransport delivery device
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United States of America Patent
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Nov 18, 2003
Grant Date -
Apr 11, 2002
app pub date -
Nov 7, 1997
filing date -
Dec 17, 1996
priority date (Note) -
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Abstract
A method is provided for preparing a novel therapeutic agent-containing reservoir (26, 28) for use in conjunction with an electrotransport drug delivery system (10). A polymeric matrix is foamed in a selected atmosphere and then cross-linked to form a polymeric closed-cell foam matrix reservoir (26, 28). The method enables relatively smaller quantities of therapeutic agent to be loaded into the electrotransport system (10) and is especially useful for the transdermal delivery of more costly drugs, such as peptides and proteins produced from genetically engineered cell lines, and/or highly potent drugs for which a small dosage is efficacious. Reservoirs (26, 28) prepared according to this method and electrotransport devices (10) containing such reservoirs are also provided.
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