US Patent No: 6,652,887

Number of patents in Portfolio can not be more than 2000

Bone graft substitute composition

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Abstract

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A composition includes calcium sulfate hemihydrate, an accelerant material, e.g., calcium sulfate dihydrate, a plasticizing material, a mixing solution, and demineralized bone matrix having a moisture content of between about 10 and about 30 weight percent.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
WRIGHT MEDICAL TECHNOLOGY, INC.ARLINGTON, TN109

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Miller, Leasa C Covington, TN 3 46
Richelsoph, Kelly Coupe Memphis, TN 5 104

Cited Art Landscape

Patent Info (Count) # Cites Year
 
MINNESOTA MINING AND MANUFACTURING COMPANY (1)
4,880,660 Method for priming hard tissue 78 1987
 
Other [Check patent profile for assignment information] (8)
5,219,897 Dental and orthopedic cement method and preforms 44 1992
5,366,507 Method for use in bone tissue regeneration 50 1992
5,236,971 Dental and orthopedic cement method and preforms 20 1992
5,769,897 Synthetic bone 124 1994
5,569,308 Methods for use in bone tissue regeneration 65 1994
5,727,945 Impregnated barrier and method of assisting bone or tissue regeneration 32 1996
5,964,805 Method and paste for articular cartilage transplantation 76 1997
5,948,426 Method and article to induce hematopoietic expansion 48 1998
 
STRYKER CORPORATION (2)
4,975,526 Bone collagen matrix for zenogenic implants 137 1989
5,162,114 Bone collagen matrix for xenogenic implants 87 1990
 
ATRIX LABORATORIES, INC. (2)
5,681,873 Biodegradable polymeric composition 150 1993
6,071,530 Method and composition for treating a bone tissue defect 69 1997
 
OSTEOMEDICAL LIMITED (1)
4,882,149 Pharmaceutical depot preparation 56 1988
 
AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (1)
5,861,445 Reinforcement of dental and other composite materials 47 1997
 
CERAMEDICAL INC. (2)
5,462,722 Calcium phosphate calcium sulfate composite implant material 66 1991
5,320,844 Composite materials for hard tissue replacement 63 1992
 
MARIEL THERAPEUTICS, INC. (1)
5,948,428 Compositions and therapeutic methods using morphogenic proteins and stimulatory factors 211 1996
 
OSTEOTECH INVESTMENT CORPORATION (4)
4,994,030 Reconstitution of human bone and tissue 54 1988
5,061,286 Osteoprosthetic implant 176 1989
5,073,373 Flowable demineralized bone powder composition and its use in bone repair 232 1989
5,405,390 Osteogenic composition and implant containing same 144 1993
 
HOSPITAL FOR JOINT DISEASES (1)
6,224,635 Implantation of surgical implants with calcium sulfate 48 1998
 
PLASMA BIOTAL LIMITED (1)
5,824,087 Bone regeneration 202 1997
 
KNC NOR ACQUISITION SUB, INC. (1)
5,697,981 Method for repairing bone 98 1995
 
WBK, INC. (1)
5,788,976 Method for effecting bone repair 50 1996
 
GENSCI REGENERATION SCIENCES INC. (1)
5,707,962 Compositions with enhanced osteogenic potential, method for making the same and therapeutic uses thereof 152 1994
 
The University of North Carolina at Chapel Hill (1)
4,619,655 Plaster of Paris as a bioresorbable scaffold in implants for bone repair 82 1984
 
MASSACHUSETTS INSTITUTE OF TECHNOLOGY (1)
5,766,618 Polymeric-hydroxyapatite bone composite 119 1997
 
INNOVASIVE DEVICES, INC. (1)
6,083,522 Devices for tissue repair and methods for preparation and use thereof 118 1998
 
LIFENET HEALTH (1)
* 6,340,477 Bone matrix composition and methods for making and using same 89 2000
 
ETHICON, INC. (2)
4,568,536 Controlled release of pharmacologically active agents from an absorbable biologically compatible putty-like composition 124 1985
4,650,665 Controlled release of pharmacologically active agents from an absorbable biologically compatible putty-like composition 85 1985
 
BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (1)
5,981,828 Composite allograft, press, and methods 72 1998
 
QUINTECH PHARMACEUTICALS, INC. (1)
4,892,734 Dispensing paste for forming medicinal pellets 22 1988
 
ASTELLAS PHARMA INC. (1)
5,830,493 Bone-forming graft 115 1997
 
UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (1)
6,051,247 Moldable bioactive compositions 85 1998
 
WARSAW ORTHOPEDIC, INC. (13)
5,290,558 Flowable demineralized bone powder composition and its use in bone repair 204 1990
5,236,456 Osteogenic composition and implant containing same 179 1991
5,484,601 Flowable demineralized bone powder composition and its use in bone repair 69 1991
5,298,254 Shaped, swollen demineralized bone and its use in bone repair 281 1991
5,284,655 Swollen demineralized bone particles, flowable osteogenic composition containing same and use of the composition in the repair of osseous defects 196 1992
5,314,476 Demineralized bone particles and flowable osteogenic composition containing same 218 1993
5,507,813 Shaped materials derived from elongate bone particles 348 1993
5,439,684 Shaped, swollen demineralized bone and its use in bone repair 323 1994
5,510,396 Process for producing flowable osteogenic composition containing demineralized bone particles 162 1994
5,676,146 Surgical implant containing a resorbable radiopaque marker and method of locating such within a body 212 1996
5,972,368 Bone graft composites and spacers 188 1997
6,037,519 Ceramic fusion implants and compositions 82 1997
5,899,939 Bone-derived implant for load-supporting applications 369 1998
 
THE REGENTS OF THE UNIVERSITY OF MICHIGAN (1)
5,763,416 Gene transfer into bone cells and tissues 112 1994
 
The Regents of the University of California (1)
4,596,574 Biodegradable porous ceramic delivery system for bone morphogenetic protein 291 1984
 
STATE STREET BANK AND TRUST COMPANY (1)
5,425,769 Composition of material for osseous repair 84 1993
 
HEXCEL CORPORATION, 94108 (1)
4,595,713 Medical putty for tissue augmentation 192 1985
 
GENZYME CORPORATION (1)
6,056,970 Compositions comprising hemostatic compounds and bioabsorbable polymers 106 1998
 
Ceskoslovenska akademie ved (1)
4,612,009 Biodegradable implant and a method for preparation thereof 116 1985
 
GENDLER FAMILY LIMITED PARTNERSHIP (1)
5,306,304 Flexible membranes produced from organic bone matrix for skeletal repair and reconstruction 98 1993
 
ED. GEISTLICH SOEHNE AG FUER CHEMISCHE INDUSTRIE (2)
5,417,975 Chemical Compound 62 1994
5,573,771 Medicinal bone mineral products 94 1995
 
UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (1)
4,681,763 Composition for stimulating bone growth 101 1985
 
Orthopaedic Research Institute, Inc., of Wichita (1)
5,336,699 Bone cement having chemically joined reinforcing fillers 100 1992
 
ZIMMER TECHNOLOGY, INC. (1)
5,512,610 Bone cement composition 44 1994
 
COLLAGEN CORPORATION (1)
4,430,760 Nonstress-bearing implantable bone prosthesis 149 1981
 
Bioscience Consultants (1)
5,531,791 Composition for repair of defects in osseous tissues, method of making, and prosthesis 152 1993
 
WRIGHT MEDICAL TECHNOLOGY, INC. (5)
5,147,403 Prosthesis implantation method 38 1989
5,614,206 Controlled dissolution pellet containing calcium sulfate 71 1995
5,756,127 Implantable bioresorbable string of calcium sulfate beads 183 1996
5,807,567 Calcium sulfate controlled release matrix 38 1996
6,030,636 Calcium sulfate controlled release matrix 37 1998
 
COLLAGEN AESTHETICS, INC. (1)
5,264,214 Composition for bone repair 97 1992
 
Sterling Drug Inc. (1)
4,820,306 Method for augmentation of the alveolar ridge 40 1984
 
NORTH SHORE UNIVERSITY HOSPITAL RESEARCH CORPORATION (1)
5,700,289 Tissue-engineered bone repair using cultured periosteal cells 113 1995
 
AWI LICENSING COMPANY (1)
5,482,551 Extruded fire resistant construction and building products 59 1994
 
MERCK PATENT GMBH (1)
6,118,043 Bone replacement material with FGF 94 1995
 
BIO HOLDINGS INTERNATIONAL LIMITED C/O MORGAN & MORGAN TRUST CORP. LTD. (1)
5,618,549 Use of particles of a biocompatible and bioabsorbable calcium salt as active ingredient in the preparation of a medicinal product intended for the local treatment of bone demineralization diseases 40 1995
 
United States Surgical Corporation (2)
5,356,629 Composition for effecting bone repair 231 1991
5,578,662 Bioabsorbable branched polymers containing units derived from dioxanone and medical/surgical devices manufactured therefrom 98 1995
 
MUSCULOSKELETAL TRANSPLANT FOUNDATION (2)
5,910,315 Allograft tissue material for filling spinal fusion cages or related surgical spaces 158 1997
6,030,635 Malleable paste for filling bone defects 163 1998
 
GENETICS INSTITUTE, LLC (1)
5,385,887 Formulations for delivery of osteogenic proteins 191 1993
* Cited By Examiner

Patent Citation Ranking

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Patent Info (Count) # Cites Year
 
Other [Check patent profile for assignment information] (1)
* 2009/0149,553 INJECTABLE RESORBABLE BONE GRAFT MATERIAL, POWDER FOR FORMING SAME AND METHODS RELATING THERETO FOR TREATING BONE DEFECTS 0 2009
 
EBI, LLC (2)
* 2008/0063,681 Therapeutic bone replacement material 4 2006
* 2010/0098,673 BONE GRAFT COMPOSITES AND METHODS OF TREATING BONE DEFECTS 10 2009
 
AGNOVOS HEALTHCARE, LLC (6)
7,754,246 Composite bone graft substitute cement and articles produced therefrom 10 2006
8,685,464 Composite bone graft substitute cement and articles produced therefrom 1 2007
8,025,903 Composite bone graft substitute cement and articles produced therefrom 3 2007
9,180,224 Composite bone graft substitute cement and articles produced therefrom 0 2010
8,685,465 Composite bone graft substitute cement and articles produced therefrom 1 2011
9,446,170 Multiphasic bone graft substitute material 0 2014
 
WRIGHT MEDICAL TECHNOLOGY, INC. (9)
* 7,291,179 Bone graft substitute composition 4 2003
* 2003/0235,621 Bone graft substitute composition 2 2003
7,507,257 Injectable resorbable bone graft material, powder for forming same and methods relating thereto for treating bone defects 1 2004
* 2004/0220,681 Injectable resorbable bone graft material, powder for forming same and methods relating thereto for treating bone defects 19 2004
7,250,550 Synthetic bone substitute material 30 2004
8,657,952 Bone graft substitute composition 1 2007
7,766,972 Synthetic, malleable bone graft substitute material 1 2007
7,658,768 Bone graft substitute composition 12 2007
8,968,465 Bone graft substitute composition 0 2014
 
GLOBUS MEDICAL, INC. (6)
7,785,634 Bone graft materials derived from mineralized gelatin 3 2006
* 2007/0202,190 Bone graft materials derived from mineralized gelatin 8 2006
7,892,577 Bone graft materials derived from mineralized gelatin 1 2006
* 2007/0202,191 BONE GRAFT MATERIALS DERIVED FROM MINERALIZED GELATIN 3 2006
* 2011/0104,299 BONE GRAFT MATERIALS DERIVED FROM MINERALIZED GELATIN 0 2011
9,138,508 Bone graft materials derived from mineralized gelatin 0 2013
 
LIDDS AB (2)
* 9,198,884 Use of carboxymethylcellulose to control ejectability and solidification time of compositions comprising one or more bioresorbable ceramics 0 2009
* 2011/0223,214 USE OF CARBOXYMETHYLCELLULOSE TO CONTROL EJECTABILITY AND SOLIDIFICATION TIME OF COMPOSITIONS COMPRISING ONE OR MORE BIORESORBABLE CERAMICS 0 2009
 
HERAEUS MEDICAL GMBH (3)
7,923,019 Antibiotic/s containing bone substitute material with sustained active substance release 1 2005
* 2006/0127,444 Antibiotic/s containing bone substitute material with sustained active substance release 2 2005
8,895,098 Coating method and coating device 0 2011
 
THE UNIVERSITY OF MEMPHIS (2)
* 7,923,021 Local delivery method and composition 1 2008
* 2009/0028,922 Local Delivery Method and Composition 0 2008
 
NUVASIVE, INC. (1)
9,272,072 Osteoinductive bone graft substitute 0 2015
 
KOREA ATOMIC ENERGY RESEARCH INSTITUTE (1)
* 2009/0004,049 Method of irradiation using process of adding vitamin C 0 2007
 
Global Medical, Inc. (1)
8,394,419 Bone graft materials derived from mineralized gelatin 0 2011
 
ORTHOVITA, INC. (7)
9,220,595 Shapeable bone graft substitute and instruments for delivery thereof 0 2004
* 2005/0288,795 Shapeable bone graft substitute and instruments for delivery thereof 31 2004
8,734,822 Composite shaped bodies and methods for their production and use 2 2004
8,685,429 Shaped bodies and methods for their production and use 0 2006
8,303,967 Bioactive bone graft substitute 7 2007
8,287,915 Bone restorative carrier mediums 7 2008
8,460,686 Bioactive bone graft substitute 0 2012
* Cited By Examiner