US Patent No: 6,652,887
Number of patents in Portfolio can not be more than 2000
Bone graft substitute composition
Stats
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Nov 25, 2003
Issued date -
Jun 24, 2002
filing date -
10/179,533
serial no -
In Force
status
Importance
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Abstract
A composition includes calcium sulfate hemihydrate, an accelerant material, e.g., calcium sulfate dihydrate, a plasticizing material, a mixing solution, and demineralized bone matrix having a moisture content of between about 10 and about 30 weight percent.
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First Claim
Related Publications
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International Classification(s)
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Cited Art
| Patent Info | (Count) | # Cites | Year |
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| 5,290,558 Flowable demineralized bone powder composition and its use in bone repair | 127 | 1990 | |
| 5,236,456 Osteogenic composition and implant containing same | 138 | 1991 | |
| 5,484,601 Flowable demineralized bone powder composition and its use in bone repair | 44 | 1991 | |
| 5,298,254 Shaped, swollen demineralized bone and its use in bone repair | 173 | 1991 | |
| 5,284,655 Swollen demineralized bone particles, flowable osteogenic composition containing same and use of the composition in the repair of osseous defects | 123 | 1992 | |
| 5,314,476 Demineralized bone particles and flowable osteogenic composition containing same | 144 | 1993 | |
| 5,507,813 Shaped materials derived from elongate bone particles | 240 | 1993 | |
| 5,439,684 Shaped, swollen demineralized bone and its use in bone repair | 197 | 1994 | |
| 5,510,396 Process for producing flowable osteogenic composition containing demineralized bone particles | 100 | 1994 | |
| 5,676,146 Surgical implant containing a resorbable radiopaque marker and method of locating such within a body | 127 | 1996 | |
| 5,972,368 Bone graft composites and spacers | 133 | 1997 | |
| 6,037,519 Ceramic fusion implants and compositions | 53 | 1997 | |
| 5,899,939 Bone-derived implant for load-supporting applications | 262 | 1998 | |
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| 5,147,403 Prosthesis implantation method | 32 | 1989 | |
| 5,614,206 Controlled dissolution pellet containing calcium sulfate | 57 | 1995 | |
| 5,756,127 Implantable bioresorbable string of calcium sulfate beads | 116 | 1996 | |
| 5,807,567 Calcium sulfate controlled release matrix | 29 | 1996 | |
| 6,030,636 Calcium sulfate controlled release matrix | 27 | 1998 | |
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| 4,994,030 Reconstitution of human bone and tissue | 34 | 1988 | |
| 5,061,286 Osteoprosthetic implant | 116 | 1989 | |
| 5,073,373 Flowable demineralized bone powder composition and its use in bone repair | 167 | 1989 | |
| 5,405,390 Osteogenic composition and implant containing same | 91 | 1993 | |
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| 4,975,526 Bone collagen matrix for zenogenic implants | 106 | 1989 | |
| 5,162,114 Bone collagen matrix for xenogenic implants | 65 | 1990 | |
| 5,948,428 Compositions and therapeutic methods using morphogenic proteins and stimulatory factors | 161 | 1996 | |
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| 5,681,873 Biodegradable polymeric composition | 96 | 1993 | |
| 6,071,530 Method and composition for treating a bone tissue defect | 49 | 1997 | |
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| 5,462,722 Calcium phosphate calcium sulfate composite implant material | 45 | 1991 | |
| 5,320,844 Composite materials for hard tissue replacement | 44 | 1992 | |
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| 5,417,975 Chemical Compound | 42 | 1994 | |
| 5,573,771 Medicinal bone mineral products | 62 | 1995 | |
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| 4,568,536 Controlled release of pharmacologically active agents from an absorbable biologically compatible putty-like composition | 116 | 1985 | |
| 4,650,665 Controlled release of pharmacologically active agents from an absorbable biologically compatible putty-like composition | 74 | 1985 | |
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| 5,910,315 Allograft tissue material for filling spinal fusion cages or related surgical spaces | 91 | 1997 | |
| 6,030,635 Malleable paste for filling bone defects | 98 | 1998 | |
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| 5,356,629 Composition for effecting bone repair | 147 | 1991 | |
| 5,578,662 Bioabsorbable branched polymers containing units derived from dioxanone and medical/surgical devices manufactured therefrom | 56 | 1995 | |
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| 5,861,445 Reinforcement of dental and other composite materials | 39 | 1997 | |
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| 5,830,493 Bone-forming graft | 70 | 1997 | |
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| 5,482,551 Extruded fire resistant construction and building products | 44 | 1994 | |
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| 5,618,549 Use of particles of a biocompatible and bioabsorbable calcium salt as active ingredient in the preparation of a medicinal product intended for the local treatment of bone demineralization diseases | 16 | 1995 | |
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| 5,531,791 Composition for repair of defects in osseous tissues, method of making, and prosthesis | 87 | 1993 | |
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| 5,981,828 Composite allograft, press, and methods | 46 | 1998 | |
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| 4,612,009 Biodegradable implant and a method for preparation thereof | 82 | 1985 | |
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| 5,264,214 Composition for bone repair | 74 | 1992 | |
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| 4,430,760 Nonstress-bearing implantable bone prosthesis | 104 | 1981 | |
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| 5,306,304 Flexible membranes produced from organic bone matrix for skeletal repair and reconstruction | 80 | 1993 | |
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| 5,385,887 Formulations for delivery of osteogenic proteins | 118 | 1993 | |
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| 5,707,962 Compositions with enhanced osteogenic potential, method for making the same and therapeutic uses thereof | 103 | 1994 | |
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| 6,056,970 Compositions comprising hemostatic compounds and bioabsorbable polymers | 51 | 1998 | |
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| 4,595,713 Medical putty for tissue augmentation | 165 | 1985 | |
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| 6,224,635 Implantation of surgical implants with calcium sulfate | 35 | 1998 | |
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| 6,083,522 Devices for tissue repair and methods for preparation and use thereof | 54 | 1998 | |
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| 5,697,981 Method for repairing bone | 85 | 1995 | |
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| 6,340,477 Bone matrix composition and methods for making and using same | 50 | 2000 | |
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| 5,766,618 Polymeric-hydroxyapatite bone composite | 67 | 1997 | |
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| 6,118,043 Bone replacement material with FGF | 74 | 1995 | |
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| 4,880,660 Method for priming hard tissue | 60 | 1987 | |
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| 5,700,289 Tissue-engineered bone repair using cultured periosteal cells | 74 | 1995 | |
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| 5,336,699 Bone cement having chemically joined reinforcing fillers | 58 | 1992 | |
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| 4,882,149 Pharmaceutical depot preparation | 38 | 1988 | |
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| 5,824,087 Bone regeneration | 96 | 1997 | |
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| 4,892,734 Dispensing paste for forming medicinal pellets | 17 | 1988 | |
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| 5,425,769 Composition of material for osseous repair | 69 | 1993 | |
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| 4,820,306 Method for augmentation of the alveolar ridge | 30 | 1984 | |
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| 4,596,574 Biodegradable porous ceramic delivery system for bone morphogenetic protein | 235 | 1984 | |
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| 5,763,416 Gene transfer into bone cells and tissues | 79 | 1994 | |
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| 4,619,655 Plaster of Paris as a bioresorbable scaffold in implants for bone repair | 59 | 1984 | |
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| 6,051,247 Moldable bioactive compositions | 59 | 1998 | |
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| 4,681,763 Composition for stimulating bone growth | 93 | 1985 | |
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| 5,788,976 Method for effecting bone repair | 31 | 1996 | |
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| 5,512,610 Bone cement composition | 26 | 1994 | |
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| 5,219,897 Dental and orthopedic cement method and preforms | 30 | 1992 | |
| 5,366,507 Method for use in bone tissue regeneration | 36 | 1992 | |
| 5,236,971 Dental and orthopedic cement method and preforms | 15 | 1992 | |
| 5,769,897 Synthetic bone | 92 | 1994 | |
| 5,569,308 Methods for use in bone tissue regeneration | 47 | 1994 | |
| 5,727,945 Impregnated barrier and method of assisting bone or tissue regeneration | 20 | 1996 | |
| 5,964,805 Method and paste for articular cartilage transplantation | 46 | 1997 | |
| 5,948,426 Method and article to induce hematopoietic expansion | 30 | 1998 | |
Patent Citation Ranking
Maintenance Fees
| Fee | Large entity fee | small entity fee | micro entity fee | due date |
|---|---|---|---|---|
| 11.5 Year Payment | $7400.00 | $3700.00 | $1850.00 | May 25, 2015 |
| Fee | Large entity fee | small entity fee | micro entity fee |
|---|---|---|---|
| Surcharge - 11.5 year - Late payment within 6 months | $160.00 | $80.00 | $40.00 |
| Surcharge after expiration - Late payment is unavoidable | $700.00 | $350.00 | $175.00 |
| Surcharge after expiration - Late payment is unintentional | $1,640.00 | $820.00 | $410.00 |