US Patent No: 6,652,887

Number of patents in Portfolio can not be more than 2000

Bone graft substitute composition

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ATTORNEY / AGENT: (SPONSORED)

Importance

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Abstract

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A composition includes calcium sulfate hemihydrate, an accelerant material, e.g., calcium sulfate dihydrate, a plasticizing material, a mixing solution, and demineralized bone matrix having a moisture content of between about 10 and about 30 weight percent.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
WRIGHT MEDICAL TECHNOLOGY, INC.ARLINGTON, TN159

International Classification(s)

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  • [Patents Count]

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Miller, Leasa C Covington, TN 5 30
Richelsoph, Kelly Coupe Memphis, TN 7 60

Cited Art Landscape

Patent Info (Count) # Cites Year
 
WARSAW ORTHOPEDIC, INC. (13)
5,290,558 Flowable demineralized bone powder composition and its use in bone repair 159 1990
5,236,456 Osteogenic composition and implant containing same 157 1991
5,484,601 Flowable demineralized bone powder composition and its use in bone repair 59 1991
5,298,254 Shaped, swollen demineralized bone and its use in bone repair 208 1991
5,284,655 Swollen demineralized bone particles, flowable osteogenic composition containing same and use of the composition in the repair of osseous defects 151 1992
5,314,476 Demineralized bone particles and flowable osteogenic composition containing same 179 1993
5,507,813 Shaped materials derived from elongate bone particles 287 1993
5,439,684 Shaped, swollen demineralized bone and its use in bone repair 241 1994
5,510,396 Process for producing flowable osteogenic composition containing demineralized bone particles 136 1994
5,676,146 Surgical implant containing a resorbable radiopaque marker and method of locating such within a body 172 1996
5,972,368 Bone graft composites and spacers 156 1997
6,037,519 Ceramic fusion implants and compositions 67 1997
5,899,939 Bone-derived implant for load-supporting applications 304 1998
 
WRIGHT MEDICAL TECHNOLOGY, INC. (5)
5,147,403 Prosthesis implantation method 36 1989
5,614,206 Controlled dissolution pellet containing calcium sulfate 63 1995
5,756,127 Implantable bioresorbable string of calcium sulfate beads 138 1996
5,807,567 Calcium sulfate controlled release matrix 33 1996
6,030,636 Calcium sulfate controlled release matrix 31 1998
 
OSTEOTECH INVESTMENT CORPORATION (4)
4,994,030 Reconstitution of human bone and tissue 44 1988
5,061,286 Osteoprosthetic implant 138 1989
5,073,373 Flowable demineralized bone powder composition and its use in bone repair 197 1989
5,405,390 Osteogenic composition and implant containing same 117 1993
 
ATRIX LABORATORIES, INC. (2)
5,681,873 Biodegradable polymeric composition 118 1993
6,071,530 Method and composition for treating a bone tissue defect 57 1997
 
CERAMEDICAL, INC. (2)
5,462,722 Calcium phosphate calcium sulfate composite implant material 55 1991
5,320,844 Composite materials for hard tissue replacement 56 1992
 
ED. GEISTLICH SOEHNE AG FUER CHEMISCHE INDUSTRIE (2)
5,417,975 Chemical Compound 51 1994
5,573,771 Medicinal bone mineral products 77 1995
 
ETHICON, INC. (2)
4,568,536 Controlled release of pharmacologically active agents from an absorbable biologically compatible putty-like composition 120 1985
4,650,665 Controlled release of pharmacologically active agents from an absorbable biologically compatible putty-like composition 81 1985
 
MUSCULOSKELETAL TRANSPLANT FOUNDATION (2)
5,910,315 Allograft tissue material for filling spinal fusion cages or related surgical spaces 116 1997
6,030,635 Malleable paste for filling bone defects 123 1998
 
STRYKER CORPORATION (2)
4,975,526 Bone collagen matrix for zenogenic implants 123 1989
5,162,114 Bone collagen matrix for xenogenic implants 79 1990
 
United States Surgical Corporation (2)
5,356,629 Composition for effecting bone repair 187 1991
5,578,662 Bioabsorbable branched polymers containing units derived from dioxanone and medical/surgical devices manufactured therefrom 75 1995
 
AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (1)
5,861,445 Reinforcement of dental and other composite materials 43 1997
 
ASTELLAS PHARMA INC. (1)
5,830,493 Bone-forming graft 89 1997
 
AWI LICENSING COMPANY (1)
5,482,551 Extruded fire resistant construction and building products 49 1994
 
BIO HOLDINGS INTERNATIONAL LIMITED C/O MORGAN & MORGAN TRUST CORP. LTD. (1)
5,618,549 Use of particles of a biocompatible and bioabsorbable calcium salt as active ingredient in the preparation of a medicinal product intended for the local treatment of bone demineralization diseases 24 1995
 
Bioscience Consultants (1)
5,531,791 Composition for repair of defects in osseous tissues, method of making, and prosthesis 118 1993
 
BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (1)
5,981,828 Composite allograft, press, and methods 56 1998
 
Ceskoslovenska akademie ved (1)
4,612,009 Biodegradable implant and a method for preparation thereof 103 1985
 
COLLAGEN AESTHETICS, INC. (1)
5,264,214 Composition for bone repair 84 1992
 
COLLAGEN CORPORATION (1)
4,430,760 Nonstress-bearing implantable bone prosthesis 127 1981
 
GENDLER FAMILY LIMITED PARTNERSHIP (1)
5,306,304 Flexible membranes produced from organic bone matrix for skeletal repair and reconstruction 89 1993
 
GENETICS INSTITUTE, LLC (1)
5,385,887 Formulations for delivery of osteogenic proteins 144 1993
 
GENSCI REGENERATION SCIENCES INC. (1)
5,707,962 Compositions with enhanced osteogenic potential, method for making the same and therapeutic uses thereof 128 1994
 
GENZYME CORPORATION (1)
6,056,970 Compositions comprising hemostatic compounds and bioabsorbable polymers 69 1998
 
HEXCEL CORPORATION, 94108 (1)
4,595,713 Medical putty for tissue augmentation 174 1985
 
HOSPITAL FOR JOINT DISEASES (1)
6,224,635 Implantation of surgical implants with calcium sulfate 42 1998
 
INNOVASIVE DEVICES, INC. (1)
6,083,522 Devices for tissue repair and methods for preparation and use thereof 72 1998
 
KNC NOR ACQUISITION SUB, INC. (1)
5,697,981 Method for repairing bone 93 1995
 
LIFENET HEALTH (1)
6,340,477 Bone matrix composition and methods for making and using same 66 2000
 
MARIEL THERAPEUTICS, INC. (1)
5,948,428 Compositions and therapeutic methods using morphogenic proteins and stimulatory factors 188 1996
 
MASSACHUSETTS INSTITUTE OF TECHNOLOGY (1)
5,766,618 Polymeric-hydroxyapatite bone composite 89 1997
 
MERCK PATENT GMBH (1)
6,118,043 Bone replacement material with FGF 86 1995
 
Minnesota Mining and Manufacturing Company (1)
4,880,660 Method for priming hard tissue 67 1987
 
NORTH SHORE UNIVERSITY HOSPITAL RESEARCH CORPORATION (1)
5,700,289 Tissue-engineered bone repair using cultured periosteal cells 92 1995
 
Orthopaedic Research Institute, Inc. (1)
5,336,699 Bone cement having chemically joined reinforcing fillers 73 1992
 
OSTEOMEDICAL LIMITED (1)
4,882,149 Pharmaceutical depot preparation 45 1988
 
PLASMA BIOTAL LIMITED (1)
5,824,087 Bone regeneration 134 1997
 
QUINTECH PHARMACEUTICALS, INC. (1)
4,892,734 Dispensing paste for forming medicinal pellets 20 1988
 
STATE STREET BANK AND TRUST COMPANY (1)
5,425,769 Composition of material for osseous repair 76 1993
 
Sterling Drug Inc. (1)
4,820,306 Method for augmentation of the alveolar ridge 34 1984
 
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (1)
4,596,574 Biodegradable porous ceramic delivery system for bone morphogenetic protein 269 1984
 
THE REGENTS OF THE UNIVERSITY OF MICHIGAN (1)
5,763,416 Gene transfer into bone cells and tissues 95 1994
 
THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (1)
4,619,655 Plaster of Paris as a bioresorbable scaffold in implants for bone repair 73 1984
 
UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (1)
6,051,247 Moldable bioactive compositions 68 1998
 
UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (1)
4,681,763 Composition for stimulating bone growth 97 1985
 
WBK, INC. (1)
5,788,976 Method for effecting bone repair 42 1996
 
ZIMMER TECHNOLOGY, INC. (1)
5,512,610 Bone cement composition 34 1994
 
Other [Check patent profile for assignment information] (8)
5,219,897 Dental and orthopedic cement method and preforms 36 1992
5,366,507 Method for use in bone tissue regeneration 46 1992
5,236,971 Dental and orthopedic cement method and preforms 18 1992
5,769,897 Synthetic bone 108 1994
5,569,308 Methods for use in bone tissue regeneration 54 1994
5,727,945 Impregnated barrier and method of assisting bone or tissue regeneration 28 1996
5,964,805 Method and paste for articular cartilage transplantation 65 1997
5,948,426 Method and article to induce hematopoietic expansion 40 1998

Patent Citation Ranking

Forward Cite Landscape

Patent Info (Count) # Cites Year
 
WRIGHT MEDICAL TECHNOLOGY, INC. (6)
7,291,179 Bone graft substitute composition 2 2003
7,507,257 Injectable resorbable bone graft material, powder for forming same and methods relating thereto for treating bone defects 0 2004
7,250,550 Synthetic bone substitute material 20 2004
8,657,952 Bone graft substitute composition 0 2007
7,766,972 Synthetic, malleable bone graft substitute material 0 2007
7,658,768 Bone graft substitute composition 8 2007
 
ORTHOVITA, INC. (5)
8,734,822 Composite shaped bodies and methods for their production and use 0 2004
8,685,429 Shaped bodies and methods for their production and use 0 2006
8,303,967 Bioactive bone graft substitute 3 2007
8,287,915 Bone restorative carrier mediums 1 2008
8,460,686 Bioactive bone graft substitute 0 2012
 
AGNOVOS HEALTHCARE, LLC (4)
7,754,246 Composite bone graft substitute cement and articles produced therefrom 4 2006
8,685,464 Composite bone graft substitute cement and articles produced therefrom 0 2007
8,025,903 Composite bone graft substitute cement and articles produced therefrom 1 2007
8,685,465 Composite bone graft substitute cement and articles produced therefrom 0 2011
 
GLOBUS MEDICAL, INC. (2)
7,785,634 Bone graft materials derived from mineralized gelatin 0 2006
7,892,577 Bone graft materials derived from mineralized gelatin 0 2006
 
Global Medical, Inc. (1)
8,394,419 Bone graft materials derived from mineralized gelatin 0 2011
 
HERAEUS MEDICAL GMBH (1)
7,923,019 Antibiotic/s containing bone substitute material with sustained active substance release 0 2005
 
THE UNIVERSITY OF MEMPHIS (1)
7,923,021 Local delivery method and composition 0 2008

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11.5 Year Payment $7400.00 $3700.00 $1850.00 May 25, 2015
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