Bone graft substitute composition

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 6652887
SERIAL NO

10179533

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A composition includes calcium sulfate hemihydrate, an accelerant material, e.g., calcium sulfate dihydrate, a plasticizing material, a mixing solution, and demineralized bone matrix having a moisture content of between about 10 and about 30 weight percent.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
WRIGHT MEDICAL TECHNOLOGY, INC.ARLINGTON, TN122

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Miller, Leasa C Covington, TN 3 49
Richelsoph, Kelly Coupe Memphis, TN 5 109

Cited Art Landscape

Patent Info (Count) # Cites Year
 
MINNESOTA MINING AND MANUFACTURING COMPANY (1)
4880660 Method for priming hard tissue 80 1987
 
Other [Check patent profile for assignment information] (8)
5219897 Dental and orthopedic cement method and preforms 45 1992
5366507 Method for use in bone tissue regeneration 51 1992
5236971 Dental and orthopedic cement method and preforms 20 1992
5769897 Synthetic bone 128 1994
5569308 Methods for use in bone tissue regeneration 67 1994
5727945 Impregnated barrier and method of assisting bone or tissue regeneration 33 1996
5964805 Method and paste for articular cartilage transplantation 77 1997
5948426 Method and article to induce hematopoietic expansion 48 1998
 
STRYKER CORPORATION (2)
4975526 Bone collagen matrix for zenogenic implants 141 1989
5162114 Bone collagen matrix for xenogenic implants 87 1990
 
ATRIX LABORATORIES, INC. (2)
5681873 Biodegradable polymeric composition 159 1993
6071530 Method and composition for treating a bone tissue defect 72 1997
 
OSTEOMEDICAL LIMITED (1)
4882149 Pharmaceutical depot preparation 57 1988
 
AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (1)
5861445 Reinforcement of dental and other composite materials 47 1997
 
CERAMEDICAL, INC. (2)
5462722 Calcium phosphate calcium sulfate composite implant material 66 1991
5320844 Composite materials for hard tissue replacement 64 1992
 
MARIEL THERAPEUTICS, INC. (1)
5948428 Compositions and therapeutic methods using morphogenic proteins and stimulatory factors 215 1996
 
OSTEOTECH INVESTMENT CORPORATION (4)
4994030 Reconstitution of human bone and tissue 57 1988
5061286 Osteoprosthetic implant 185 1989
5073373 Flowable demineralized bone powder composition and its use in bone repair 237 1989
5405390 Osteogenic composition and implant containing same 148 1993
 
Hospital for Joint Diseases (1)
6224635 Implantation of surgical implants with calcium sulfate 49 1998
 
PLASMA BIOTAL LIMITED (1)
5824087 Bone regeneration 210 1997
 
KNC NOR ACQUISITION SUB, INC. (1)
5697981 Method for repairing bone 99 1995
 
WBK, INC. (1)
5788976 Method for effecting bone repair 54 1996
 
GENSCI REGENERATION SCIENCES INC. (1)
5707962 Compositions with enhanced osteogenic potential, method for making the same and therapeutic uses thereof 156 1994
 
The University of North Carolina at Chapel Hill (1)
4619655 Plaster of Paris as a bioresorbable scaffold in implants for bone repair 83 1984
 
MASSACHUSETTS INSTITUTE OF TECHNOLOGY (1)
5766618 Polymeric-hydroxyapatite bone composite 126 1997
 
INNOVASIVE DEVICES, INC. (1)
6083522 Devices for tissue repair and methods for preparation and use thereof 130 1998
 
LIFENET HEALTH (1)
* 6340477 Bone matrix composition and methods for making and using same 93 2000
 
ETHICON, INC. (2)
4568536 Controlled release of pharmacologically active agents from an absorbable biologically compatible putty-like composition 126 1985
4650665 Controlled release of pharmacologically active agents from an absorbable biologically compatible putty-like composition 87 1985
 
BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (1)
5981828 Composite allograft, press, and methods 76 1998
 
QUINTECH PHARMACEUTICALS, INC. (1)
4892734 Dispensing paste for forming medicinal pellets 22 1988
 
The United States of America as represented by the Secretary of the Air Force (1)
6051247 Moldable bioactive compositions 86 1998
 
ASTELLAS PHARMA INC. (1)
5830493 Bone-forming graft 119 1997
 
WARSAW ORTHOPEDIC, INC. (13)
5290558 Flowable demineralized bone powder composition and its use in bone repair 214 1990
5236456 Osteogenic composition and implant containing same 183 1991
5484601 Flowable demineralized bone powder composition and its use in bone repair 72 1991
5298254 Shaped, swollen demineralized bone and its use in bone repair 302 1991
5284655 Swollen demineralized bone particles, flowable osteogenic composition containing same and use of the composition in the repair of osseous defects 210 1992
5314476 Demineralized bone particles and flowable osteogenic composition containing same 227 1993
5507813 Shaped materials derived from elongate bone particles 370 1993
5439684 Shaped, swollen demineralized bone and its use in bone repair 353 1994
5510396 Process for producing flowable osteogenic composition containing demineralized bone particles 166 1994
5676146 Surgical implant containing a resorbable radiopaque marker and method of locating such within a body 233 1996
5972368 Bone graft composites and spacers 197 1997
6037519 Ceramic fusion implants and compositions 84 1997
5899939 Bone-derived implant for load-supporting applications 385 1998
 
THE REGENTS OF THE UNIVERSITY OF MICHIGAN (1)
5763416 Gene transfer into bone cells and tissues 116 1994
 
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (1)
4596574 Biodegradable porous ceramic delivery system for bone morphogenetic protein 294 1984
 
STATE STREET BANK AND TRUST COMPANY (1)
5425769 Composition of material for osseous repair 85 1993
 
HEXCEL CORPORATION, 94108 (1)
4595713 Medical putty for tissue augmentation 196 1985
 
GENZYME CORPORATION (1)
6056970 Compositions comprising hemostatic compounds and bioabsorbable polymers 119 1998
 
Ceskoslovenska akademie ved (1)
4612009 Biodegradable implant and a method for preparation thereof 118 1985
 
GENDLER FAMILY LIMITED PARTNERSHIP (1)
5306304 Flexible membranes produced from organic bone matrix for skeletal repair and reconstruction 99 1993
 
ED. GEISTLICH SOEHNE AG FUER CHEMISCHE INDUSTRIE (2)
5417975 Chemical Compound 63 1994
5573771 Medicinal bone mineral products 95 1995
 
UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (1)
4681763 Composition for stimulating bone growth 101 1985
 
Orthopaedic Research Institute, Inc. (1)
5336699 Bone cement having chemically joined reinforcing fillers 102 1992
 
ZIMMER TECHNOLOGY, INC. (1)
5512610 Bone cement composition 46 1994
 
COLLAGEN CORPORATION (1)
4430760 Nonstress-bearing implantable bone prosthesis 152 1981
 
Bioscience Consultants (1)
5531791 Composition for repair of defects in osseous tissues, method of making, and prosthesis 161 1993
 
WRIGHT MEDICAL TECHNOLOGY, INC. (5)
5147403 Prosthesis implantation method 38 1989
5614206 Controlled dissolution pellet containing calcium sulfate 71 1995
5756127 Implantable bioresorbable string of calcium sulfate beads 193 1996
5807567 Calcium sulfate controlled release matrix 38 1996
6030636 Calcium sulfate controlled release matrix 38 1998
 
COLLAGEN AESTHETICS, INC. (1)
5264214 Composition for bone repair 100 1992
 
Sterling Drug Inc. (1)
4820306 Method for augmentation of the alveolar ridge 41 1984
 
NORTH SHORE UNIVERSITY HOSPITAL RESEARCH CORPORATION (1)
5700289 Tissue-engineered bone repair using cultured periosteal cells 119 1995
 
AWI LICENSING COMPANY (1)
5482551 Extruded fire resistant construction and building products 60 1994
 
MERCK PATENT GMBH (1)
6118043 Bone replacement material with FGF 94 1995
 
BIO HOLDINGS INTERNATIONAL LIMITED C/O MORGAN & MORGAN TRUST CORP. LTD. (1)
5618549 Use of particles of a biocompatible and bioabsorbable calcium salt as active ingredient in the preparation of a medicinal product intended for the local treatment of bone demineralization diseases 41 1995
 
UNITED STATES SURGICAL CORPORATION (2)
5356629 Composition for effecting bone repair 238 1991
5578662 Bioabsorbable branched polymers containing units derived from dioxanone and medical/surgical devices manufactured therefrom 106 1995
 
MUSCULOSKELETAL TRANSPLANT FOUNDATION (2)
5910315 Allograft tissue material for filling spinal fusion cages or related surgical spaces 166 1997
6030635 Malleable paste for filling bone defects 170 1998
 
GENETICS INSTITUTE, LLC (1)
5385887 Formulations for delivery of osteogenic proteins 199 1993
* Cited By Examiner

Patent Citation Ranking

Forward Cite Landscape

Patent Info (Count) # Cites Year
 
EBI, LLC (2)
* 2008/0063,681 Therapeutic bone replacement material 5 2006
* 2010/0098,673 BONE GRAFT COMPOSITES AND METHODS OF TREATING BONE DEFECTS 14 2009
 
AGNOVOS HEALTHCARE, LLC (7)
7754246 Composite bone graft substitute cement and articles produced therefrom 12 2006
8685464 Composite bone graft substitute cement and articles produced therefrom 1 2007
8025903 Composite bone graft substitute cement and articles produced therefrom 3 2007
9180224 Composite bone graft substitute cement and articles produced therefrom 0 2010
9550010 Methods of treating degenerative bone conditions 0 2011
8685465 Composite bone graft substitute cement and articles produced therefrom 1 2011
9446170 Multiphasic bone graft substitute material 0 2014
 
WRIGHT MEDICAL TECHNOLOGY, INC. (10)
* 7291179 Bone graft substitute composition 5 2003
* 2003/0235,621 Bone graft substitute composition 2 2003
7507257 Injectable resorbable bone graft material, powder for forming same and methods relating thereto for treating bone defects 2 2004
* 2004/0220,681 Injectable resorbable bone graft material, powder for forming same and methods relating thereto for treating bone defects 19 2004
7250550 Synthetic bone substitute material 33 2004
8657952 Bone graft substitute composition 1 2007
7766972 Synthetic, malleable bone graft substitute material 1 2007
7658768 Bone graft substitute composition 13 2007
* 2009/0149,553 INJECTABLE RESORBABLE BONE GRAFT MATERIAL, POWDER FOR FORMING SAME AND METHODS RELATING THERETO FOR TREATING BONE DEFECTS 0 2009
8968465 Bone graft substitute composition 0 2014
 
GLOBUS MEDICAL, INC. (6)
7785634 Bone graft materials derived from mineralized gelatin 9 2006
* 2007/0202,190 Bone graft materials derived from mineralized gelatin 8 2006
7892577 Bone graft materials derived from mineralized gelatin 1 2006
* 2007/0202,191 BONE GRAFT MATERIALS DERIVED FROM MINERALIZED GELATIN 3 2006
* 2011/0104,299 BONE GRAFT MATERIALS DERIVED FROM MINERALIZED GELATIN 0 2011
9138508 Bone graft materials derived from mineralized gelatin 0 2013
 
LIDDS AB (2)
* 9198884 Use of carboxymethylcellulose to control ejectability and solidification time of compositions comprising one or more bioresorbable ceramics 0 2009
* 2011/0223,214 USE OF CARBOXYMETHYLCELLULOSE TO CONTROL EJECTABILITY AND SOLIDIFICATION TIME OF COMPOSITIONS COMPRISING ONE OR MORE BIORESORBABLE CERAMICS 0 2009
 
HERAEUS MEDICAL GMBH (3)
7923019 Antibiotic/s containing bone substitute material with sustained active substance release 1 2005
* 2006/0127,444 Antibiotic/s containing bone substitute material with sustained active substance release 2 2005
8895098 Coating method and coating device 0 2011
 
THE UNIVERSITY OF MEMPHIS (2)
* 7923021 Local delivery method and composition 1 2008
* 2009/0028,922 Local Delivery Method and Composition 0 2008
 
NUVASIVE, INC. (1)
9272072 Osteoinductive bone graft substitute 0 2015
 
KOREA ATOMIC ENERGY RESEARCH INSTITUTE (1)
* 2009/0004,049 Method of irradiation using process of adding vitamin C 0 2007
 
Global Medical, Inc. (1)
8394419 Bone graft materials derived from mineralized gelatin 0 2011
 
ORTHOVITA, INC. (7)
9220595 Shapeable bone graft substitute and instruments for delivery thereof 0 2004
* 2005/0288,795 Shapeable bone graft substitute and instruments for delivery thereof 33 2004
8734822 Composite shaped bodies and methods for their production and use 2 2004
8685429 Shaped bodies and methods for their production and use 4 2006
8303967 Bioactive bone graft substitute 12 2007
8287915 Bone restorative carrier mediums 12 2008
8460686 Bioactive bone graft substitute 4 2012
* Cited By Examiner