Method of treating cancer using immunostimulatory oligonucleotides

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United States of America Patent

PATENT NO 6653292
SERIAL NO

09337619

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Abstract

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Nucleic acid sequences containing unmethylated CpG dinucleotides that modulate an immune response including stimulating a Th1 pattern of immune activation, cytokine production, NK lytic activity, and B cell proliferation are disclosed. The sequences are also useful a synthetic adjuvant.

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Patent Owner(s)

Patent OwnerAddress
UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY DEPARTMENT OF HEALTH AND HUMAN SERVICES THEFDA/CBER BUILDING 29A 3D10 BETHESDA MD 20892

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Krieg, Arthur M Iowa City, IA 154 11149
Weiher, George Iowa City, IA 1 111

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