Skin and muscle-targeted gene therapy by pulsed electrical field
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United States of America Patent
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Nov 25, 2003
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Jul 26, 2000
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Jul 13, 1998
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Abstract
The present invention describes an in vivo method, using pulsed electric field to deliver therapeutic agents into cells of the skin and muscle for local and systemic treatments. In particular, therapeutic agents include naked or formulated nucleic acid, polypeptides and chemotherapeutic agents.
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