Bioprosthetic heart valves

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 6660260
SERIAL NO

09399704

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention provides methods and materials related to heart valves and the treatment of valvular heart disease. Specifically, the invention provides non-murine heart valve cells and heart valve cusps as well as methods for making heart valves. The invention also provides methods and materials for (1) slowing heart valve degeneration, thrombosis, and calcification, (2) treating carcinoid heart disease, (3) identifying inhibitors of heart valve degeneration, thrombosis, and calcification, and (4) determining the safety of drugs.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCHROCHESTER, MN756

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Rajamannan, Nalini M Rochester, MN 7 7

Cited Art Landscape

Patent Info (Count) # Cites Year
 
DUKE UNIVERSITY (1)
5880102 Adenoviral vector system 29 1995
 
BAXTER INTERNATIONAL INC. (1)
6060640 Multiple-layer, formed-in-place immunoisolation membrane structures for implantation of cells in host tissue 60 1995
 
EDWARDS LIFESCIENCES CORPORATION (1)
5928281 Tissue heart valves 178 1997
 
NitroMed, Inc. (1)
* 6087479 Localized use of nitric oxide-adducts to prevent internal tissue damage 108 1995
 
ADVANCED RESEARCH AND TECHNOLOGY INSTITUTE, INC. (1)
5797870 Pericardial delivery of therapeutic and diagnostic agents 153 1995
 
GABBAY, SHLOMO (1)
5935163 Natural tissue heart valve prosthesis 177 1998
 
ST. JUDE MEDICAL, INC. (2)
* 5855620 Matrix substrate for a viable body tissue-derived prosthesis and method for making the same 65 1996
* 6193749 Calcification-resistant biomaterials 27 1997
 
Comedicus Incorporated (1)
* 5650447 Nitric oxide-releasing polymers to treat restenosis and related disorders 85 1994
 
SYMBION, INC. (1)
4477930 Natural tissue heat valve and method of making same 157 1982
 
ELI LILLY AND COMPANY (1)
4762842 Selective method for blocking 5HT2 receptors 13 1987
* Cited By Examiner

Patent Citation Ranking

Forward Cite Landscape

Patent Info (Count) # Cites Year
 
MEDICIS PHARMACEUTICAL CORPORATION (1)
6949646 Imidazonaphthyridines 2 2004
 
Concievalve LLc (1)
* 2014/0257,473 METHODS FOR INHIBITING STENOSIS, OBSTRUCTION, OR CALCIFICATION OF A STENTED HEART VALVE OR BIOPROSTHESIS 13 2014
 
EDWARDS LIFESCIENCES AG (2)
8142495 System and a method for altering the geometry of the heart 53 2007
8591576 Method for altering the geometry of the heart 22 2012
* Cited By Examiner