US Patent No: 6,660,260

Number of patents in Portfolio can not be more than 2000

Bioprosthetic heart valves

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Abstract

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The invention provides methods and materials related to heart valves and the treatment of valvular heart disease. Specifically, the invention provides non-murine heart valve cells and heart valve cusps as well as methods for making heart valves. The invention also provides methods and materials for (1) slowing heart valve degeneration, thrombosis, and calcification, (2) treating carcinoid heart disease, (3) identifying inhibitors of heart valve degeneration, thrombosis, and calcification, and (4) determining the safety of drugs.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCHROCHESTER, MN617

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Rajamannan, Nalini M Chicago, IL 8 7

Cited Art Landscape

Patent Info (Count) # Cites Year
 
DUKE UNIVERSITY (1)
5,880,102 Adenoviral vector system 25 1995
 
BAXTER INTERNATIONAL INC. (1)
6,060,640 Multiple-layer, formed-in-place immunoisolation membrane structures for implantation of cells in host tissue 46 1995
 
EDWARDS LIFESCIENCES CORPORATION (1)
5,928,281 Tissue heart valves 127 1997
 
NITROMED, INC. (1)
* 6,087,479 Localized use of nitric oxide-adducts to prevent internal tissue damage 94 1995
 
ADVANCED RESEARCH AND TECHNOLOGY INSTITUTE, INC. (1)
5,797,870 Pericardial delivery of therapeutic and diagnostic agents 136 1995
 
GABBAY, SHLOMO (1)
5,935,163 Natural tissue heart valve prosthesis 95 1998
 
ST. JUDE MEDICAL, INC. (2)
* 5,855,620 Matrix substrate for a viable body tissue-derived prosthesis and method for making the same 49 1996
* 6,193,749 Calcification-resistant biomaterials 20 1997
 
Comedicus Incorporated (1)
* 5,650,447 Nitric oxide-releasing polymers to treat restenosis and related disorders 72 1994
 
SYMBION, INC. (1)
4,477,930 Natural tissue heat valve and method of making same 112 1982
 
Eli Lilly and Company (1)
4,762,842 Selective method for blocking 5HT2 receptors 13 1987
* Cited By Examiner

Patent Citation Ranking

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Patent Info (Count) # Cites Year
 
MEDICIS PHARMACEUTICAL CORPORATION (1)
6,949,646 Imidazonaphthyridines 2 2004
 
EDWARDS LIFESCIENCES AG (2)
8,142,495 System and a method for altering the geometry of the heart 18 2007
8,591,576 Method for altering the geometry of the heart 2 2012
* Cited By Examiner

Maintenance Fees

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11.5 Year Payment $7400.00 $3700.00 $1850.00 Jun 9, 2015
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Surcharge - 11.5 year - Late payment within 6 months $160.00 $80.00 $40.00
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