Methods and reagents for vaccination which generate a CD8 T cell immune response
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United States of America Patent
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Dec 16, 2003
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app pub date -
Dec 9, 1999
filing date -
Jun 9, 1997
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Abstract
New methods and reagents for vaccination are described which generate a CD8 T cell immune response against malarial and other antigens such as viral and tumour antigens. Novel vaccination regimes are described which employ a priming composition and a boosting composition, the boosting composition comprising a non-replicating or replication-impaired pox virus vector carrying at least one CD8 T cell epitope which is also present in the priming composition.
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