Nucleic acids encoding hedgehog proteins
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United States of America Patent
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Dec 16, 2003
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N/A
app pub date -
Dec 13, 2000
filing date -
Dec 30, 1993
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Expired
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Abstract
The present invention concerns the discovery that proteins encoded by a family of vertebrate genes, termed here hedgehog-related genes, comprise morphogenic signals produced by tissue patterning centers, and are involved in the formation of ordered spatial arrangements of differentiated tissues in vertebrates. The present invention makes available compositions and methods that can be utilized, for example to generate and/or maintain an array of different vertebrate tissue both in vitro and in vivo.
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