Pharmaceutical compositions and treatment methods
Number of patents in Portfolio can not be more than 2000
United States of America Patent
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Dec 23, 2003
Issued Date -
N/A
app pub date -
Mar 23, 2000
filing date -
Mar 16, 2000
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The invention provides compositions comprising, 16.alpha.-bromo-3.beta.-hydroxy-5.alpha.-androstan-17-one hemihydrate and one or more excipients, typically wherein the composition comprises less than about 3% water. The compositions are useful to make improved pharmaceutical formulations. The invention also provides methods of intermittent dosing of steroid compounds such as analogs of 16.alpha.-bromo-3.beta.-hydroxy-5.alpha.-androstan-17-one and compositions useful in such dosing regimens. The invention further provides compositions and methods to inhibit pathogen (viral) replication, ameliorate symptoms associated with immune dysregulation and to modulate immune responses in a subject using certain steroids and steroid analogs. The invention also provides methods to make and use these immunomodulatory compositions and formulations.
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