Recombinant Streptomyces hygroscopicus host cells that produce 17-desmethylrapamycin
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United States of America Patent
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Dec 30, 2003
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N/A
app pub date -
Oct 30, 2000
filing date -
Oct 29, 1999
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Abstract
Recombinant host cells that produce rapamycin analogues are constructed by deleting or modifying rapamycin biosynthetic gene cluster genes and are useful in the production of compounds used as antifungals, anticancers, immunosuppressants, and neurotrophins.
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