US Patent No: 6,677,145

Number of patents in Portfolio can not be more than 2000

Elongase genes and uses thereof

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ALSO PUBLISHED AS: 20020138874
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Abstract

The subject invention relates to the identification of several genes involved in the elongation of polyunsaturated acids (i.e., "elongases") and to uses thereof. At least two of these genes are also involved in the elongation of monounsaturated fatty acids. In particular, elongase is utilized in the conversion of gamma linolenic acid (GLA) to dihomogamma linolenic acid (DGLA) and in the conversion of AA to adrenic acid (ADA), or eicosapentaenoic acid (EPA) to .omega.3-docosapentaenoic acid (DPA). DGLA may be utilized in the production of polyunsaturated fatty acids, such as arachidonic acid (AA), docosahexaenoic acid (DHA), EPA, adrenic acid, .omega.6-docosapentaenoic acid or .omega.3-docosapentaenoic acid which may be added to pharmaceutical compositions, nutritional compositions, animal feeds, as well as other products such as cosmetics.

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First Claim

Related Publications

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Patent Owner(s)

Patent OwnerAddressTotal Patents
ABBOTT LABORATORIESABBOTT PARK, IL2621

International Classification(s)

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  • [Patents Count]

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Huang, Yung-Sheng Upper Arlington, OH 82 617
Leonard, Amanda Eun-Yeong Gahanna, OH 19 145
Mukerji, Pradip Columbus, OH 83 568
Pereira, Suzette L Westerville, OH 32 127

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Patent Citation Ranking

Forward Cites

Patent Info (Count) # Cites Year
 
DSM IP ASSETS B.V. (28)
7,642,074 PUFA polyketide synthase systems and uses thereof 1 2007
7,759,548 Polyunsaturated fatty acid production in heterologous organisms using PUFA polyketide synthase systems 2 2007
7,939,716 PUFA polyketide synthase systems and uses thereof 1 2007
7,906,706 PUFA polyketide synthase systems and uses thereof 1 2007
7,902,427 PUFA polyketide synthase systems and uses thereof 1 2007
7,803,620 Pufa polyketide synthase systems and uses thereof 1 2007
7,626,009 PUFA polyketide synthase systems and uses thereof 1 2007
7,601,522 PUFA polyketide synthase systems and uses thereof 2 2007
7,960,524 PUFA polyketide synthase systems and uses thereof 1 2007
7,842,796 PUFA polyketide synthase systems and uses thereof 1 2007
7,816,504 PUFA polyketide synthase systems and uses thereof 1 2007
7,608,703 PUFA polyketide synthase systems and uses thereof 2 2007
7,608,702 PUFA polyketide synthase systems and uses thereof 2 2007
8,003,772 Chimeric PUFA polyketide synthase systems and uses thereof 2 2007
7,897,844 PUFA polyketide synthase systems and uses thereof 1 2007
7,973,149 PUFA polyketide synthase systems and uses thereof 1 2007
7,919,320 PUFA polyketide synthase systems and uses thereof 1 2007
7,807,442 PUFA polyketide synthase systems and uses thereof 1 2007
7,605,245 PUFA polyketide synthase systems and uses thereof 2 2007
7,897,391 PUFA polyketide synthase systems and uses thereof 1 2007
7,897,392 PUFA polyketide synthase systems and uses thereof 1 2007
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7,718,431 PUFA polyketide synthase systems and uses thereof 1 2007
7,629,450 PUFA polyketide synthase systems and uses thereof 1 2007
7,560,539 PUFA polyketide synthase systems and uses thereof 3 2007
8,426,686 Polyunsaturated fatty acid production in heterologous organisms using PUFA polyketide synthase systems 0 2010
 
E. I. DU PONT DE NEMOURS AND COMPANY (12)
7,238,482 Production of polyunsaturated fatty acids in oleaginous yeasts 10 2004
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7,470,532 Mortierella alpina C.sub.16/18 fatty acid elongase 1 2005
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8,049,062 Delta-9-elongases and their use in making polyunsaturated fatty acids 0 2006
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COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (7)
7,834,250 Synthesis of long-chain polyunsaturated fatty acids by recombinant cells 4 2005
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SUNTORY HOLDINGS LIMITED (1)
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THE UNIVERSITY OF BRISTOL (1)
7,714,185 Method for the production of polyunsaturated fatty acids 5 2003
 
Other [Check patent profile for assignment information] (1)
8,465,787 Delta-9 fatty acid elongase genes and their use in making polyunsaturated fatty acids 0 2012

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