P2X7 receptor-deficient mice and uses thereof

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 6677501
APP PUB NO 20020007498A1
SERIAL NO

09875318

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Abstract

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The invention provides non-human, genetically-modified mammals and genetically modified animals cells having a functionally disrupted P.sub.2.times.7 receptor gene. Also provided are methods for producing genetically modified mice in which one or both P.sub.2.times.7 R alleles have been functionally inactivated.

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Patent Owner(s)

Patent OwnerAddress
NORTH CAROLINA UNIVERSITY OF CHAPEL HILL7027 THURSTON-BOWLES BUILDING DEPARTMENT OF MEDICINE CB #7248 CHAPEL HILL NC 27599

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gabel, Christopher A Ledyard, CT 10 66
Koller, Beverly H Chapel Hill, NC 8 454

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