Disaccharides with anti-arthrosic properties
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United States of America Patent
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Jan 20, 2004
Grant Date -
Sep 25, 2003
app pub date -
Jan 10, 2003
filing date -
Jul 13, 2000
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Abstract
The invention relates to novel disaccharides of formula (I), wherein R.sup.1 is selected from the group consisting of hydrogen, linear or branched (C.sub.1 -C.sub.4) alkyl, phenylalkyl with less than ten carbon atoms and --COCH.sub.3 ; R.sup.2 is selected from the group consisting of hydrogen, --COCH.sub.3 and SO.sub.3 M; R.sup.3 is selected from the group consisting of hydrogen, linear or branched (C.sub.1 -C.sub.4) alkyl, phenylalkyl with less than ten carbon atoms, --COCH.sub.3 and y --COPh, Ph being phenyl; G is selected from amongst --COOR.sup.4 and --COOM, R.sup.4 is selected from the group consisting of hydrogen, (C.sub.1 -C.sub.2)-alkyl and arylalkyl with less than sixteen carbon atom; A is selected from the group consisting of hydrogen, --SO.sub.3 H, --SO.sub.3 M and --COCH.sub.3 ; B is selected from the group consisting of hydrogen, --SO.sub.3 H, --SO.sub.3 M and --COCH.sub.3, wherein either A or B are necessarily either --SO.sub.3 H or --SO.sub.3 M, M being a an organic or metallic cation. Said compounds can be used as anti-arthritic agents, anti-inflammatory agents or to control blood coagulation. ##STR1##
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